Conserved Protein Domain Family
DUF6235
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pfam19748: DUF6235 
Family of unknown function (DUF6235)
This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001503) is described by MIBiG as an example of the following biosynthetic class, polyketide. It includes a member from the amycolamycin A biosynthetic gene cluster from Amycolatopsis sp.. This family appears to be predominantly found in Actinobacteria.
Links
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Statistics
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PSSM-Id: 498244
Aligned: 7 rows
Threshold Bit Score: 135.584
Created: 20-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
EHR52741      17 PQAAFSLRTGSDILGDWSATATHREREAVYAALFSMVDGSLFHAYEVMDDFQLPSELFVLVPNRLVIKIRINFLGS-FSI 95 
1_pfamImport   1 MAMRLQLTSGLQVLEEWAINAPQADRNVIYEALFAVADGSAFLIYDIFGDGRDPHQFIILVKHDLVIRIGLKRTDSsFEI 80 
OKJ81151      11 RRPAFRLVAGWDLLEQWSGTANQIEKNAVHQALFAVVDRTVFRTYSTSEVTSQPQEFFVRLRQGLVLKIRIRDFDM-FEI 89 
PRH80819     267 KPLGLRLGSGWDLLERWSGAAHQIERNAVHKALFAVVDRSVFTAYETLEDAARPREFFVRLREDLVLKLRVRDLDV-FEI 345
WP_013228624   1 MAVRLQLAAGVEVLERWAESAPQAERNIVYEALFAVGDGSAFLVYDIFGDPRDPGNFLVMVKPGLVLKIMVQRAQSaFEI 80  Amycolatopsis m...
WP_133794681   4 ERMRLKLNLGLARLEKWAGSAGQVEKNALYKALFAVADGTVYNTYKVLDDVARDGEFFVVVRENLIVKICFREPDV-FGV 82  Actinokineospor...
WP_094863879   8 ERKRCRLTTGLQRLELWAATADQGERNRVYDVLFAVADGSVFWRYRVMRDAHRPGEFSVVVRDDLIVKVDFPAPAC-FAI 86  Amycolatopsis a...

EHR52741      96 VRIGY-----REEFSDLFFTRR 112
1_pfamImport  81 VYIGAlehgtPAAAWADDVDGS 102
OKJ81151      90 AYVGP-----VGETPGIDLETG 106
PRH80819     346 VYVGS-----VGEAPGIDLGTG 362
WP_013228624  81 RYVGA---------IDDDLGVR 93  Amycolatopsis mediterranei
WP_133794681  83 LYIGA-----PEEAAETEVEIT 99  Actinokineospora alba
WP_094863879  87 LYVGT-----RGNAEGLDVDVD 103 Amycolatopsis antarctica
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