pfam19732: SpoIIE_N (This model is not part of the current CDD release)
Stage II sporulation protein E N-terminal
This is the N-terminal domain found in Stage II sporulation protein E which includes the 10 transmembrane domains and the regulatory domain, the latter located adjacent the PP2C phosphatase domain. The regulatory domain mediates the formation of dimers between SpoIIE molecules, required for phosphatase activation. An N-terminal 45-residue long alpha-helix makes intramolecular contacts with the switch helices (alpha1 and alpha2) of the phosphatase domain.
Jiyao W et al.(2023). "The conserved domain database in 2023.",