Conserved Protein Domain Family
DUF6215
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pfam19721: DUF6215 (This model is not part of the current CDD release)
Family of unknown function (DUF6215)
This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001856) is described by MIBiG as an example of the following biosynthetic class, polyketide. It includes a member from the caniferolide A biosynthetic gene cluster from Streptomyces caniferus. This family appears to be predominantly found in Actinobacteria.
Links
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Statistics
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PSSM-Id: 523745
Aligned: 34 rows
Threshold Bit Score: 79.6697
Created: 20-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
WP_067244498  12 GRGPNAWVQVISAFVVV---AALAGGLWKAQKDHVARedaAAaAPv-GPISCS----SAAPTGVPtMVRAgvkyVSANQL 83  Streptomyces sp...
WP_099503897   9 KKSMSAGAQAAAAVVVV---AGVMGGMWGLGEVLQGK---PD-DG--EPADCS----ISSTQDAL-PSKY----VSGAQL 70  Streptomyces
WP_103549641   9 RRGLNAGVQTFAAVALV---AGVAGGVGGLWRIIPKG---DG-AD--GPATCA-------DGHGTpPAKR----VSGAQL 68  Streptomyces po...
WP_093497137   9 EKDGRPGLQAIAAVALF---AVVVGALWAQKEFVHQK---DA-VG--EPAACS-----NPDDHL--PARY----VSGGRL 68  Streptomyces sp...
WP_019072901   9 EKGMRAGAQAVAAIVVV---GGVVGGLWGLGGVLPKT---TQ-DT--KPAICS-----ASTDKTL-PAKY----VSPTAL 69  Streptomyces
WP_085209372   9 EKGMRAGAQVVAAVVLV---GGVAGLMWALAALPQGA---AE-DE--RPAACS-----TSTTEPPpPELRvpgvVSGDRL 74  Streptomyces sp...
WP_067443420   9 EKRPNAAAQAITAVVLI---GGIGAALWGLDPRETQA---AD-----EPATCS----PASTAESR-PSGN----VSGDQL 68  Streptomyces li...
WP_318277813  32 GATPRVGLQVGAAVVLV---GVLFAGLWVLAGRERDGv---------APAKCTaateKDSPKYPA--------------L 85  Kitasatospora a...
WP_110671033  57 GWTLGPSGRAAVTMALGvvvALVMAGLYVKAHPSTGSs---------GPAACEapksTDSREYPA--------------L 113 Streptomyces ta...
WP_104818564   9 GRGAKVAGVVAAAVVTLg-sVGLMVG-WGTGAIGGLPtlgGAgATaaGPAACKapvaEDPPGYPA--------------L 72  Kitasatospora s...

WP_067244498  84 CQALNRPDLAALLGTPGERALSYSGDDDSVTL-GGSDVPAPEMNVTLRTYSVELSASFDHFAVQDMAGLLGGD 155 Streptomyces sp. DSM 1...
WP_099503897  71 CTALNRPDLPTLLGTPEERAETAGGSDSWITLaGGTEIAAPEANVALKTYSVKLSASYGRLPVAQEADYLGET 143 Streptomyces
WP_103549641  69 CRALNRSDLPVLLGTPDEHARTADGDDGWITLdGGTRIASPEANVTLKTYSVKLSASEDRFSVSQGLDLLPKa 141 Streptomyces populi
WP_093497137  69 CKALNRPDLPALLGTSDEQAETAHGSGEWLTLaGGTKIAEPEATVTLETYSVKLTASYDHMTVATAGDLMDDa 141 Streptomyces sp. Ag109...
WP_019072901  70 CTALNRADLPVLLGTPDEHAETASGSAGWMTLaGGTKIASPEADVDLRTYSVRLSASYDDIPVAQAARYVDST 142 Streptomyces
WP_085209372  75 CTALNRADLASLLGTPQEHTETADGHDFSFELaAGSKIAIPEATVTLDTYSVKITATYDGLPVEGSEDLLGGG 147 Streptomyces sp. Amel2...
WP_067443420  69 CTALNRPDLATLLGTPTEKAKTAGGSDSYFTSgDGTKTATPSGEVTFETYTVKLSATYDGLAVAEEGEYLGRT 141 Streptomyces lincolnensis
WP_318277813  86 CAALNRPDQPVLVGVPEERVLVAQPGLSAALGpGLTKEDYGSAEVQFRELYVELADH-GDVDVADFPSPGDPT 157 Kitasatospora aureofac...
WP_110671033 114 CAALNRPDLPALLGTPQARVSIAQSGGGPLTSpDG-KELSASAQVQLGPVCVSLSDH-HIASVEDILGFASLV 184 Streptomyces tateyamensis
WP_104818564  73 CAAFNRPDLPVLVGAPTERVSNAHSASSVTTGaDGKKAGAPAVEVQIGAVDVRVEDV-PGLSLEDYKLFTTpt 144 Kitasatospora sp. MMS1...
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