Conserved Protein Domain Family
DUF6208
?
pfam19713: DUF6208 
Family of unknown function (DUF6208)
This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0000976) is described by MIBiG as an example of the following biosynthetic classes, NRP (non-ribosomal peptide) and polyketide. It includes a member from the curacin A biosynthetic gene cluster from Moorea producens 3L. This family appears to be predominantly found in Cyanobacteria.
Links
?
Statistics
?
PSSM-Id: 498215
Aligned: 8 rows
Threshold Bit Score: 457.657
Created: 20-Feb-2025
Updated: 28-Apr-2025
Structure
?
Aligned Rows:
Download Cn3D
PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
WP_013321939   2 TQKTSTIFEIPLALL----SFLFYKAMKFLIGNLYTIYLT-------FNKSKASQWRVLSEEvVIKTALSLPVLMTKGPR 70  Gloeothece verr...
WP_015193348   1 MNNIVLIGEITLALL----SFIFYKIMKFLIGNLFTLYLA-------TNKKKASQWRVLSQE-TINSFLSLPVLMTKGPR 68  Stanieria cyano...
BAZ46398       1 MKTILLGWEIILALL----SFVFYKVMKFIIGNIYTIYLI-------INKKQASQWRVLSQK-MINSPLILAVLMTKGPR 68 
WP_006511284   1 MGKLILIWEIPLAIL----SFVFYKITKFLIGNLFTIYLV-------LNKSKASMWRFISRK-MLDSPLILPVLMTKGPR 68  Xenococcus sp. ...
WP_012599250   8 LSIVELFLELPLTLL----SFVFYKVMKFMIGNLYTVYLT-------FNKSKTSQWRVLSEE-VIKSALSVPVLMTKGPR 75  Gloeothece citr...
WP_104372975   1 MRRIVNWFSIPFQIVisacSYGFVYVMRWVLRKI-----NkeggimlLGKHESLSWQGWSKS--QTRTWGLPYVMIVAPR 73  Desulfocucumis ...
WP_133111707   1 MESICLVWRLPLSVL----SFFFYRIVRFCLQKVVRKEVRr-----rSSLGEPVHWLGLSEA--LKQPMGLVYIMVTGPR 69  Candidatus Scal...
WP_254658119  57 NNRFSLIGEIPLAIL----SLFFYKAMKFIVGNLYTFYLT-------VDKKKTFQWRVLSAE-NLKSSLSLPVLMTKGPR 124 Pleurocapsa sp....

WP_013321939  71 WNTHAIIGTL-GPFNVNQSIAIDLNSANQTTRSWIAVIYSFPGYETIASLESNRINPQ------EQWASLALKPGKYSIG 143 Gloeothece verr...
WP_015193348  69 WNTHAIIGTL-GPFAVQKSISIDLQSANNSAGSWIAVVYSFPTYRTITSLESHQINST------KSWQSIELKPGKYSLG 141 Stanieria cyano...
BAZ46398      69 WNTHATIGTL-GPFSVKESIEIDIVSASKSALSWIAVVYSFPGYRTITSLESEKINRNqdnnvsNSWETIKLAPGKYSLG 147
WP_006511284  69 WNTHAIIGTL-GPFKVEQEVSLNIATANSSARSWIAVIYSFPGYKTITSLESSKISTN------NDWYSIKLPTGKYSFG 141 Xenococcus sp. ...
WP_012599250  76 WNTHAIIGTL-GPFSVNQSIAIDLNSVNQTSQSWIAVIYNFPQYETITSLESNRINSD------NQWACLTLKPGKYSIG 148 Gloeothece citr...
WP_104372975  74 WNPHSVQHHV-GPLEVSGEILIHVETARKSAKQWIISFYR--HGREVSTLSSMKCTNH------DSWQSVMLTPGTYAIF 144 Desulfocucumis ...
WP_133111707  70 WNCSAVIGVLgGSLKVESSIDIQIEAANRSAKQWTLVIYN-ECHQTVAYVGSMNTAEG------TEWQKVNLEEGLYSIG 142 Candidatus Scal...
WP_254658119 125 WNTHAIIGTL-GPFSVKESIALDTESAKNSAGSWIAVIYSFPSYQTITSLESDRLNSQ------DKWETLKLKPGKYSIG 197 Pleurocapsa sp....

WP_013321939 144 LRYYNWGEKVIVPTVKVDDQIFVESQSIPSDINKFYL---DLIQKKNWFYLSLHYYIFTLLRLRKRLPESLIKQEYLPVG 220 Gloeothece verr...
WP_015193348 142 LRYYNWRNSINLPAIKIDNQDFVSATDVPNNINDFYH---NLIQAKNWFYLSLHYYIFTILKLRKWLPESFVRYEFLPVG 218 Stanieria cyano...
BAZ46398     148 VRFYNRLDNITYPAIKVDKELFAESYSVPNNINDYYY---DLIKAKNWFYSSLHYYIFTILKLRNYLPESFVRREFLPVG 224
WP_006511284 142 LRYYNRLNKITLPAIKIDDNILTDSQEVPVNNNDFYH---DLIKAKSWFYSSLHYYIFTILKLRNFLPESFVRKEFLPVG 218 Xenococcus sp. ...
WP_012599250 149 LRYYNWGEKVVFPSIKVEDKVFVDPQVIPSEVNQFYS---SLINYKNWFYLSLHYYIFTLLRLRKILPDSFVKQEYLPVG 225 Gloeothece citr...
WP_104372975 145 LRYYNWDKNGECPAVKIDNKLQIPPCPIEPEIESYEKfmsDLKHRGNGFYCFLHYYVLKTLQWHKHLPGKFVRKAYLPFG 224 Desulfocucumis ...
WP_133111707 143 LRYYNCSHDVKFPAVRVDNIERVSCRSMNNEMQEYQTylkQIENKRGFFYYCLHYYMFHMLRWNKFFSASLVTSEFLPVG 222 Candidatus Scal...
WP_254658119 198 LRYYQWRDRVNLPAVTIDGVEFVSSCPVPSDTNNFYY---DLIKHKNWFYLALHYYIFTILRLRKYLPESFVRNEYLPVG 274 Pleurocapsa sp....

WP_013321939 221 ATDTEFVYNYLTRGQALQISLDSDLVKNYDIYLTIYDRSSLPLTWSQITEENYLTKPIENNGYYLIRMRPKYVSleeVLK 300 Gloeothece verr...
WP_015193348 219 APATEFFYNYLTKTQTLQLEFSNSLIQDYDIYFTIYDRSSLPLNYCQIKTEKYTLPATGMNGYYLLRIRPKPNT---TLE 295 Stanieria cyano...
BAZ46398     225 APATHFAYNYLDSQQALIINIIPEVIAEFDIYFTLYDRSSLPLTWCAIENLEYQLPPQANKGYFLLRVRPKPQY---ADT 301
WP_006511284 219 APDTFFAYNYLGKRQSLKLDFAQEIIDNCNIYFNLYDRSSLPLSWCEISTTEHNIAAPETNSYYLLRIRPQPGL---SFD 295 Xenococcus sp. ...
WP_012599250 226 ATDTEFVYNYLLKGQALQITLDSELVKNYDIYLTIYDRSSLPLSWDRIIEDKYLTKPIENNGYYLIRMRPKYTSleeILT 305 Gloeothece citr...
WP_104372975 225 NAGTIFYYGLLDKGEVLQIDYPQSLSEKASVYLVVLDTCGFPVFWLMLAKTRFVSDEMPRNGTYLIRI------------ 292 Desulfocucumis ...
WP_133111707 223 NPETLFEYGCLTKGNSLHVDFEADVLDRAYIYLAYYNTCSFPVFWIRIDQTGYLSQTVPCDGYYLIRV------------ 290 Candidatus Scal...
WP_254658119 275 APDTQFVYGYLMRGQSLQIESNSSLVKNYNIYLTLYDRSSLPLFWSKIESEKFLTQPIENHGFYLIRLRSKPNLegnSAI 354 Pleurocapsa sp....

WP_013321939 301 QLPVQSVISDEETLTQKLKLT 321 Gloeothece verrucosa
WP_015193348 296 QVSFNSQLIEENNQLQHWLLQ 316 Stanieria cyanosphaera
BAZ46398     302 KIKVISQLTAIEDTIQRWQIS 322
WP_006511284 296 TSKIQFQIVTENDLSQQALLK 316 Xenococcus sp. PCC 7305
WP_012599250 306 ELPVESQISDETELIQQLKLK 326 Gloeothece citriformis
WP_104372975 293 ---IYNKFKDYHAAVRNIEYC 310 Desulfocucumis palustris
WP_133111707 291 ---VYKNEVESATSSKKIQCK 308 Candidatus Scalindua japonica
WP_254658119 355 KLPIESQLKDEDSLVQRLQIF 375 Pleurocapsa sp. PCC 7327
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap