Conserved Protein Domain Family
DUF6187
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pfam19685: DUF6187 
Family of unknown function (DUF6187)
This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001503) is described by MIBiG as an example of the following biosynthetic class, polyketide. It includes a member from the amycolamycin A biosynthetic gene cluster from Amycolatopsis sp.. This family appears to be predominantly found in Actinobacteria.
Links
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Statistics
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PSSM-Id: 437517
Aligned: 6 rows
Threshold Bit Score: 158.795
Created: 20-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
WP_073721167   6 GYDSRFSLTAVDEPALTETGVMLMGLDAERLLAGLGLATLADDPAQVALAVDRVRHDVpAFPGFDALVDVGARHWRSTRA 85  unclassified St...
WP_091382284   1 MSDTSFDLPALDDPASTETGIMLLGLDPDRLLACLAVVTLADDAGQVAMLVDHVRHGG-AELTMPDLVAAGARRWRSIRP 79  Actinokineospor...
WP_054047940   1 MSDTRFTLPAIDAPASTETGVMLLGLDPERLLACLAVVTLADDPGQVAMLVDHVRHGG-AHLTMPDLITAGAHHWRTIRP 79  Alloactinosynne...
WP_073896312   7 SFDTRFSLTPVDESGTTETGVLLMGLEAERLLAGLGLAALADDPAQVLIAVDRIRHGVrATMTFEALVEAGAQRWRETRP 86  unclassified St...
WP_016332239   4 PYDSRFTLPSIDDAPSTESGVILLGLDAERLLAGVGLARLADEPALVALAVDQARHEA-LDLGLGALVEAGIVRWRAVRP 82  Amycolatopsis k...
WP_013228621   4 RGDLRFVLPDVEAPAAVEAGVILLGLDADRLLAGLGLARLADDAALVTQVVDQARHEA-GGFGFAALVASGAGCWRELR- 81  Amycolatopsis m...

WP_073721167  86 VIAAAGSRPPAPASLRRAWDETLRMLTYCDLGdSGSATIAHLAACWLRQEEIDRFARRPALTG 148 unclassified Streptomyces
WP_091382284  80 ELADADPSPSTSASLRQAWERSHRTLTTVFST-VGPAGVVYLTACWLRRADIDNLVATLGGTP 141 Actinokineospora alba
WP_054047940  80 DLAAADPNPVVSAAVRQTWDRAHTAIAAELTT-VGPARLVYLTVCWLRRADIDPVAALSGGEP 141 Alloactinosynnema sp. L-07
WP_073896312  87 ALAAAVGPASPPAALRKALKDTLRIFAHCDLGdPGPATSAHLAACWLRRNEIDRLAQCPAHGE 149 unclassified Streptomyces
WP_016332239  83 -LIEAGPEMTAAGSLRREWEHATARVTATVTG-LGPASVACLAACWLRRDDVDEFAAHGRAPE 143 Amycolatopsis keratiniphila
WP_013228621  82 AFAGDGRSTASPGALRREWEVAHALATAAVPG-AGAATIAHLTACSLRRADVDPLADRYADGT 143 Amycolatopsis mediterranei
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