Conserved Protein Domain Family
DUF6186
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pfam19684: DUF6186 
Family of unknown function (DUF6186)
This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001215) is described by MIBiG as an example of the following biosynthetic class, NRP (non-ribosomal peptide). It includes a member from the conglobatin biosynthetic gene cluster from Streptomyces conglobatus. This family appears to be predominantly found in Actinobacteria.
Links
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Statistics
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PSSM-Id: 498192
Aligned: 28 rows
Threshold Bit Score: 33.4529
Created: 20-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
SCG48063      29 SRIPPLGVVCGCLMRYDvgpvpVGRIGLLGFWWWVGWHFLAR 70 
WP_117377344  39 RGPVRAAEAVEAALRTT-----PGRVLVLVAWVWLGVHFLAR 75  Geodermatophilus sp. LHW52908
SCG38925     113 RRLAPLSEMLIAASRTV-----AGRAVVLGVWLWLGWHFLAR 149
WP_121157520  30 STVAPLGNALIAAMRTG-----TGRLIVLGTWLWMGWHFLAR 66  Micromonospora pisi
WP_095563999  35 RWPAPLGTALSAALRST-----VGRLLVFGWWLWIGWHFLAR 71  Plantactinospora sp. KBS50
WP_125806822  30 SGVRPFSTTLAAALRSR-----GGRVVVFGAWLWLGWHFLAR 66  Actinoplanes sp. ATCC 53533
WP_014349192  30 DTLAPLGTVIALALRTR-----TARLIMLPVWVWLGWHFLAR 66  Nocardia cyriacigeorgica
WP_025351558  30 RSWATLGETVRYLTRTR-----LARIAAVAVWAWLGWHFLAR 66  Nocardia nova
WP_097245673  30 DLLTPLSAVAAAALTSR-----PVRIIAVLCWAWLGWHFLAR 66  Nocardia amikacinitolerans
WP_067511537  30 DLLAPLGVVVGAALRGR-----AMRLVAVAGWIWLGWHFLAR 66  Nocardia puris
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