CCY82243 1 MDFLLKAL-ANFIGNFLKgLI-ENVLAGVTDTfQALMKTYVTHs-------L---VTDAHMAVVSVSIALIILFCVKQYF 68 CCY73704 1 MTFIIISLiVALLGGIVTlFFsSEMVGELYTT-VFDCGQYLTTvsg---veF---FSLLMPVSYGFGISLIILKFLKKAF 73 WP_014355518 2 FDIFLGFLgDFMNNGSSAfASnTTSIKSLADN-VFYIDRWIGDttq---mdF---FSGMSTVVFEMAMWLLILKFLRNGF 74 Acetobacterium ... WP_092755476 1 MTDILKNFiLDIIGDTGNiF--DVTITNFVMI-VFYADKSIQGilg---neIifdFGKVWTIIYSAGLSLLGVKCMRKGF 74 Hydrogenoanaero... WP_092485245 1 MEVIYNLItGAIVN-----FF-AGIADSMINMaMLEVTNLMKVamdvldnpL---VRNAIGISQAAAGSLLAVAVTVECL 71 Desulfoscipio g... WP_104373482 8 IWEGFVNVlAKLYNNLVT-SLtGGMLNSMAAAlQILDSTY---------------VRNVIVDAQVIGGSLLTLKILYDTL 71 Desulfocucumis ... WP_012268836 13 VTNFFQNLlESLVSMF------TSFFGDEMAV-ALKiln----------tpY---ITNGIKLAQIIAGTLLALKVAAEAL 72 Thermoanaerobacter WP_013296852 13 VTNFFSNIlDSLLSLFVS-FLgDEMALALKILnTPY-------------------ITNAIYFTKLIAGTLLGVKVAAEAL 72 Thermoanaerobac... WP_013275256 1 MNVISNLInTAITD-----FI-TNLLDSILSVfVAFAGDEMALalkiletpY---VVNAISLSRTLAGSLLGVKVAAEAV 71 Thermosediminib... 2_pfamImport 1 AELLQQFLtVF-----------GAIFDNIFVVvAEFNKd------------I---ASGVTDFTLPFSIAFIVFLTIKQYF 54
CCY82243 69 GTYVMETSGDPQADPLDIL--VRGAEATAITTCSS--WFFFSFMNFCSAFAEQIVK-GAGEeDFTV-----TFNSAvegl 138 CCY73704 74 DIYVLWTDGDPDADPFLLL--TNFVRAVGTALIFQ--WLYGLFVDICREITNTIIS-QING-GTDM-----T-TEWvtai 141 WP_014355518 75 ETYISETGGDPDASPMAMV--ARFVKAIVLAVSFP--VLYEFFARICISFLMMLLD-SSSL-PLS------ENSNLltqi 142 Acetobacterium ... WP_092755476 75 DQYILWTDGDADTPPLEMV--VKLGKAIAIAVCFP--TLYKWLVDIMTGFTNKLLA-AITP-LPVQs---sTIFSIlqss 145 Hydrogenoanaero... WP_092485245 72 RSYILYQHGEPGADIGRLL--TRAALGAAAIAGMP------WLAEFVYKLGNSLAG-AIGT-ISSYei-erGFEGVslgs 140 Desulfoscipio g... WP_104373482 72 YTYILRANGEP-TDPGGLL--FRVSMAAAVVGGAP--WIARQVYSACTDLATEIAG-SQAIdSSQLs----PFVALtn-- 139 Desulfocucumis ... WP_012268836 73 KTYILYNSGDSSAQPLELV--KRTAFAAAMVSTSP--WLVTKVYTFGADLAKEVAA-LPAV-KLEN-----PVLNIvsdi 141 Thermoanaerobacter WP_013296852 73 KAYILYTSGDSSARPFELVkrTGFAALMVSAGPWAvsTIYEWGTELAKAVASLPST-QANN-PVA------GLQNIlsel 144 Thermoanaerobac... WP_013275256 72 KSYILYSSGDPGADPLNLLrrTAFSAFMIGAGPWAvtNVYKFGGELARAVAKLPST------NADN-----PLNTIfsls 140 Thermosediminib... 2_pfamImport 55 TVYVLETDGDPDADPLDIF--LRAAQAIAVAVCCD--WIFDFFLQFSSSFTFDLQSnALNTgGQEVsdtltELLSIpanf 130
CCY82243 139 ivnittgGFVWLLFLLATLIGIFVFYVIAAIRAIELALMYIVLPLFAAELCYANHERFNGLVTSIIVTGLYFSLQLLMFS 218 CCY73704 142 ----tsmGIVPAIAGLIFVICWLILYFSFMARGIEMMVMQIGVPLACVGLLDNDKGVFRAYINQFVKAFVTTIVQIMLCK 217 WP_014355518 143 ----ttaS-TSGLANFVFWIGFLILYFQLLKRGAELLVLRLCFPIACVGLIESDNGAYAPFMMMIFKTGMTTVIQIALFQ 217 Acetobacterium ... WP_092755476 146 pmdsaksAFLGALVMLIYLILIVIIVFQFFKKGVEMLVLRLGVPFGIVGYIDSDQGIAKPYFRIFYQCAFTVMIQVVLFK 225 Hydrogenoanaero... WP_092485245 141 ---aldmPVTLVIMVLIVLVLWFLILVQAAIRGVELGALAVVGPVMAIGLLKNDEGVFATWWRELVVLSMTQALQVLLIK 217 Desulfoscipio g... WP_104373482 140 ------pGVIITLVAIAGLVLWILILIQTGVRAVELAVLSITGSVMAVGLTSPDQGTFAAWWRELVVLSMSQVIQIFLVK 213 Desulfocucumis ... WP_012268836 142 ----sqmSTALLLILLAVIVIWILILIQTAIRAVEIAFIAVSGPIMAVGLTRPDEGVWSVWWRELVVLSLSQAVQTFMIR 217 Thermoanaerobacter WP_013296852 145 ----ssfSSAVIFIALIALVVWILILVQTGIRAVEIAFLSVSAPIMAVGLTRPDEGVWTVWWRELIVLSLSQAVQTFMIR 220 Thermoanaerobac... WP_013275256 141 ----asfSAALVVTSFAAVIIWALILIQTGIRAVEIAFLAVSGPIMAVGLTRPDEGVWSAWWRELIVLSLSQAVQTFMIR 216 Thermosediminib... 2_pfamImport 131 ----qsiPAVIIIIAIGVTVAIIIFGISAGIRGAELILFKMLFPLFACDLLTTSRERWNGFFTSYMVTWLAYGLQLVSFN 206
CCY82243 219 LflnqFVDTLSGisasstMNLg-----tFTTI-----GFLVAMLRSPRWLEKFAYNTGVg-dAVKRGSMTVTSSVLTSTM 287 CCY73704 218 I----GLSLMLNatiisaSNI-------FWGI-----ACMIAAISMPKILREFLVPTTGdgrIGTTVSQTVHIASMAKNI 281 WP_014355518 218 L----SYKMISS------YDI-------LIGF-----IFLILAITAPKFLQQFMVPSGGgg-gANKALTVARISEVAVRA 274 Acetobacterium ... WP_092755476 226 F----SIGLWMRc-----ENP-------AWAI-----AVMMAAVSTPKFISQFLVQSGGgggASSSIYLVSNLASRAASL 284 Hydrogenoanaero... WP_092485245 218 GflaqGVNMASD------FGP-------YFAI-----AWLWVTFKAPSFLRQFAHHTG----IGSAAGGAAKMILVRKML 275 Desulfoscipio g... WP_104373482 214 G----ALSSLTLvsvgtvMQM-------FFFL-----GWLWVAYRTPAVLRQFAYSTGIggaAAGTAQQAGYLLIMRRIF 277 Desulfocucumis ... WP_012268836 218 G----FLSTIAN------MYFtseilskLMLI-----GWLWVAFKTPSVLRQFAYHSGVggaVGQAAQSAGSMYIMRKMI 282 Thermoanaerobacter WP_013296852 221 GflstGVNMQFSsp---vLNL-------LMLI-----GWLWVAFKTPAVLRQFAYHTGMg-sAVGQAGQSAGSMYILRKA 284 Thermoanaerobac... WP_013275256 217 GflstAANIFFSsp---mLNM-------LMLI-----GWLWVAFKTPAVLRQFAYHSGMg-sAIGHAGQTAGSMYILRRM 280 Thermosediminib... 2_pfamImport 207 Mfa-sTLTVFIT------ADTt-----dFWKLfaimvGWLLLMLRAPKWLEKFTYTSG----LASGVHGAGR--SLMYMG 268
CCY82243 288 LR 289 CCY73704 282 IA 283 WP_014355518 275 IK 276 Acetobacterium woodii WP_092755476 285 FG 286 Hydrogenoanaerobacterium saccharovorans WP_092485245 276 TR 277 Desulfoscipio geothermicus WP_104373482 278 TR 279 Desulfocucumis palustris WP_012268836 283 MK 284 Thermoanaerobacter WP_013296852 285 IL 286 Thermoanaerobacterium thermosaccharolyticum WP_013275256 281 MM 282 Thermosediminibacter oceani 2_pfamImport 269 MK 270
Jiyao W et al.(2023). "The conserved domain database in 2023.",