Conserved Protein Domain Family
HTH_58
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pfam19575: HTH_58 (This model is not part of the current CDD release)
Helix-turn-helix domain
This family of proteins is functionally uncharacterized. However, it contains a helix-turn-helix domain which strongly suggests these proteins are transcriptional regulators. This family of proteins is primarily found in actinobacteria. Proteins in this family are typically between 69 and 86 amino acids in length.
Links
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Statistics
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PSSM-Id: 523720
Aligned: 44 rows
Threshold Bit Score: 77.2374
Created: 20-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
WP_106582885   5 LRKGTRVTGSDRSDLATELKRRYESGESIRSLAASTGRSYGFVHRLLSESGVSLRGRGGATR 66  Murinocardiopsis flavida
WP_185056765   4 LRKHARVAGAERESLKADLKRRYAAGESIRELAASTGRSYGFVHRLLVEAGALLRPRGRVRR 65  Thermocatellispora tengchongensis
WP_067825317   5 LARGTRVTGAERTQLAAELAPRYAAGESIRDLAAETGRSYGFIYNVLKEAGVTLRGRGGNTR 66  Actinomadura
WP_256764243  10 LGRGARITGAERERVAAELAARYGRGESIRFMADDLGRSYGWVQGLLKEAGVTLRGRGGATR 71  Luteococcus japonicus
WP_232530639  12 LTKGARITGDQRSSLGTTFGQRYAGGESIRSIAQDTGRSYGFVHGVLKESGATLRGRGGATR 73  Microlunatus antarcticus
WP_231930365   5 LARGSRITGTQRAELAARLGRRYAAGESIRAIAEDAGRSFGFVHGLVKESGVDLRGRGGATR 66  Friedmanniella luteola
WP_179756219  14 LAKGSRITGAQRDTLASQFSKRYASGESIRKIADDAGRSFGFVHGVLVEAGVELRGRGGATR 75  Microlunatus parietis
WP_013862359   4 VVRGARITGAQREKLAAQYVKKYESGQSIRQIADKAGRSYGFVHGVLVESGIALRGRGGATR 65  Microlunatus phosphovorus
WP_016670186   4 ITKGQRISGEQRQQLMSEFVERYRAGETIRQLAESSGRSYGFVQGMLKEAGVSFRSRGGAHR 65  Propionibacterium sp. oral taxon 192
WP_246044402  11 LAAGVRIVGDQRESLAMELSLRYAAGESIRSLADSTGRSYGFIQSLLKESGVEFRPRGGATR 72  Propioniferax innocua
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