Conserved Protein Domain Family
DUF6073
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pfam19550: DUF6073 
Family of unknown function (DUF6073)
This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001804) is described by MIBiG as an example of the following biosynthetic class, polyketide. This family includes a protein from the tiancimycin biosynthetic gene cluster from Streptomyces sp. CB03234 and appears to be predominantly found in bacteria.
Links
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Statistics
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PSSM-Id: 437382
Aligned: 5 rows
Threshold Bit Score: 333.006
Created: 20-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
WP_017742117   1 MTAADTlknhhSKKLAWGPQIDLNGLDYLYPPQAVEPYTPPVPGVDNLGITSTDTFLVPSIGEFTVNFQGYVRVARSQP- 79  Scytonema hofma...
WP_073759213   1 MSTETQ-----QPSVVFGRPVTTDGVPNRYSGTDVTPWTPPVPGIDNLGITSVDTFAVPGVGEYTVSFSGFVRVVRSEP- 74  Streptomyces sp...
WP_073381048   1 MS---------EKKTLLGRPVETEGVPNLYEGSPVVKWKAPEPGIDNLGLHSWDTFAIPGVGEFDVEFDGYVRVVRSPA- 70  Nocardiopsis fl...
WP_277750700  11 LVENEQsaalsSAEVVKGHEAAWGGEGNLYP---IRPYTLTSASLEAFTVRERIHVRVEGLGEDIVDLHGMAVYRRHDPk 87  Nonomuraea poly...
WP_091088507  16 IATDFDaatlsSAEVVKGHASAWGGPGNLYP---IRPYTLTPSALETFIVRERIHVRIDGLGEDIVDLHGMAIYRRHDPh 92  Nonomuraea

WP_017742117  80 ----TTNHWNTAEVFTNLIDMCMRGEAPGIGSIIVTLNPDILSTGQLR-TPYADINCEKP-AKACRMAVGALFNLPQLNM 153 Scytonema hofma...
WP_073759213  75 ----TSEEWSNAEVYTNLIEMKMEGSCEELGPITVTLNPDCLSAGQIR-TPFDPYAGEGPaAKACRMAVGAIFDMPKLGL 149 Streptomyces sp...
WP_073381048  71 ----TDEEWAGAEVYTNLIEMHMTGASEELGTITVTLNPEYLSAGQIR-TPFDPYAGEGPaAKACRMAVGCMFDIPKLGT 145 Nocardiopsis fl...
WP_277750700  88 aadgQPLTWANSTITAQFLALQVTGHSEVFGQVRVSNSPGKAEGARVKpSPPPEDHGIQP-IKDCITMLYPRFEVEELGT 166 Nonomuraea poly...
WP_091088507  93 s--aTEMDWSSSTITAQFLSLQVTGHSELFGQVKVSNTPSKSEGARVKpAPDTGDGTTMP-IKDCITMIYPRFEVEQLGT 169 Nonomuraea

WP_017742117 154 TLFNKEPIELTIDDVRAIPPAGNPGNGQIYHILPLFDLSNPDGAPAAYLTGLKFTMGHYVTEAKIQ 219 Scytonema hofmannii
WP_073759213 150 KLVNKEPIILTIDDVRQIPPAGSPGKGQIYRMLPLHDIKRQEDSPIAYVTSLRFTMGGYLPKEQFG 215 Streptomyces sp. CB03234
WP_073381048 146 RLFNREPVILTIDDVRSIPPAGAPGKGQIYRMLPLYDVRTPWDQPTAYLTSLKFNMGGYLPPERFQ 211 Nocardiopsis flavescens
WP_277750700 167 TIDTGSKIVRLESRVAMVPPIGDVSRTS--QSYTLFD---PEGRQVGELIAADIEIGSLIHHVPIQ 227 Nonomuraea polychroma
WP_091088507 170 TVDTGDQVVRLESRVAMVPPIGDVSRTS--RSYALYD---SEGRQLGELLAADIEIGNLLHHVPIA 230 Nonomuraea
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