Conserved Protein Domain Family
DUF6069
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pfam19545: DUF6069 (This model is not part of the current CDD release)
Family of unknown function (DUF6069)
This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0001769) is described by MIBiG as an example of the following biosynthetic class, polyketide. This family includes a protein from the family saquayamycin A biosynthetic gene cluster from Streptomyces sp. and appears to be predominantly found in Actinobacteria.
Links
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Statistics
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PSSM-Id: 523716
Aligned: 90 rows
Threshold Bit Score: 37.9763
Created: 20-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
WP_111490108   12 AAPGTRRRTRALAVLGGVVAAFAVWVVAVpVLGV---DLDARmgsgsgadPQRVGPGAVLVASLLVGLAGWGLLALLERG 88  Peterkaempfera...
WP_012921888    8 PIVRVAGRRRLAVVAVTSAAALATWAILGpLAGV---DFQAKqg----saTIQVSGVSVFVAATAMAFAGWGLLALLERR 80  Kribbella flavida
jgi:Snas_2062  10 PVPANRRRVWILSIVAAVSLPTALWTIVDpLAGH---ELvaas----ggqTMHVTLPWVIAGAMAPGMIGLGLSMVLRRL 82 
WP_009283703    9 PSVGRVLSLAAIAGVISAIVNVLLFQIGL-ATGAipgDLIIPn------aGEPLSAVPVLIASLLPSLVAGLVLVILNRF 81  Fibrisoma limi
jgi:Caur_0715  33 IDLRRLPRATIIGAVIGVVINLIIYGAAR-AAGL---EFRAPvpp--tneLMPLPVIAVITATVVPAIGAALVLALLSRF 106
WP_104433193   10 PSRPAWWQAVGAGVLGAVAVNLVLYLFAR-AAGA---SLALPdg----sgTHVVGVPDVVGATVVPLLVGTVLAVLLSRR 81  Kineococcus xi...
WP_094363843   14 TAPRGLARAVLPAAGIALVANLIVYAAAR-ALGV---DLLVQppt--attPEQVTAIPVAVMSVVPMLLALLLALAVRRW 87  Enemella dayho...
WP_105548997   11 FKMPFNYVQVLIAAFGAIVTSIFVYFVSE-TAGA---SMffs-----gglFPHLTIQEIAGFIFPTFVILGFLTFLIGRA 81  Arthrobacter s...
2_pfamImport    1 FDAGRLWAGGVATALVAGLISVVGILVARgLLGV---PVLAPqge---gaWGNASTMTYCVACAVVALGATGLAQVLLAT 74 
WP_106537806   13 VDAGRLWAGGGASALVAALIAVAGIVIVRaLFDV---PVLAPegd---gvWGNANTWWYAIGAAVAALAATGLVHVLVNT 86  Haloactinopoly...

WP_111490108   89 ApErARTRWTAVAVVVLVLSLA-GPL-PGGATTAAKVALTCMHLAAGAVLIPLLSRSATR 146 Peterkaempfera bronchialis
WP_012921888   81 T-AnARKPWTVVAVIACVLSLG-SPL-TGGIGIGSKLGLALLHLVVGAVVILGLRRTALS 137 Kribbella flavida
jgi:Snas_2062  83 TkH-SRIVWLIVSILALAGSLG-SPL--GGTTTTTVLVLMTMHLMVGAAIIPGGLKLTTR 138
WP_009283703   82 TrN-PLRLFNIVAAVIVLLSFF-SPFsIPNVPIGMVVILELMHVVVAGVVVFTFNRFARS 139 Fibrisoma limi
jgi:Caur_0715 107 TaR-PLRIFLICAAVVLVISFA-GPF-TLPVSLLEQMVLNLMHVVAAGAIVWALVRYT-S 162
WP_104433193   82 WpV-LLRVAQVGGAVVALVTVA-GPL-TGDTDAATRLVLAAMHVVSAVAVVAILEGVHRG 138 Kineococcus xinjiangensis
WP_094363843   88 ----APRSWLVLAWLGLAVGVVsMPV-FAQATPATKVALSLMHLITGALWWLRVRAAARR 142 Enemella dayhoffiae
WP_105548997   82 SpR-FCKVAQWLGVAIAVISMI-NPI-LFAQDLASGIGLAVIHLVVGASWYLAVNYSNKK 138 Arthrobacter sp. MYb227
2_pfamImport   75 TpN-GARFFGWIMVLLTAIAVV-LPL-SVDFDPESKVFTAVLNLVIGLVVTVLVRGVVTS 131
WP_106537806   87 TpR-PLRFFGWVIGLVTVIAAV-APF-TPDAELSAQLATSAINVVIGVAIGSLVSGSAHS 143 Haloactinopolyspora alba
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