Conserved Protein Domain Family
DUF6035
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pfam19500: DUF6035 
Family of unknown function (DUF6035)
This family of proteins is functionally uncharacterized. This family of proteins is found in Proteobacteria and Bacteroidetes. Proteins in this family are typically between 425 and 520 amino acids in length. There is a conserved GVD sequence motif. This family contains a PD-(D/E)XK nuclease domain.
Links
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Statistics
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PSSM-Id: 437332
Aligned: 3 rows
Threshold Bit Score: 567.329
Created: 20-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
OFY17739      11 AFDKISGEILNADEIFYNKKDAFLIRRQFhedkvelycceceqrlhvstskhdrlhFKHQPKADFCILKDGNLSPQEVDQ 90 
WP_060386420   1 MDNSTNNKNIFQSELPCEKKNGHSIIQEF---------------------------INNYPYGVQDLIKLLECGYQITYE 53  Bacteroides ste...
WP_094997437  10 AFDKTSGEILEADDVFDTAKNSFELRRQYhrdevelycceceqklnvsgskydrlhFKHQPNAAFCYLKETDLSQEETEQ 89  Maribacter coba...

OFY17739      91 HNKILVAK---ESERHKKLKNKIASLLQN-----------VKGVDNASISIDNKVIIKNNErrrpdvycKYLDKELVFEI 156
WP_060386420  54 DRKIMKEQfptDTYKYYATFSRLAFKLYQegqaelittliTSGVDLSGTIYTIEALLSNKP--------EYFSFQTNVWV 125 Bacteroides ste...
WP_094997437  90 LAQLYRGK---ESARHKTLKNKIAEKLYN-----------LDGVD--SICVDDTFIYDGNEkrrpdvycKYLDKELVFEI 153 Maribacter coba...

OFY17739     157 QLSDLSLRYilsrydfYRQNkmfliWILDNFDVHKQAQLERDIKYLTKYENFFNLDENTkefslNCTYKFPFLTDDNSLL 236
WP_060386420 126 CIANNAITH-------YKNH-----WIFCEAALKQSGKWEEVYKAESFLRKHNKLDKNE-----IIAWKKPKEYKILKLL 188 Bacteroides ste...
WP_094997437 154 QLSDLSLRYiydrhdfYKRKgvfliWILDDFDVHGRRQMERDIKYLTDFQNFFKLDESSepfrlLCTYKYPFLTEDNKLL 233 Maribacter coba...

OFY17739     237 TKWLNKSIPFHELKFDSECYQIYYYNFgDNKTLKEKEQWQNAKQIKEVEKIKIEEDRLSAAKYKSKRI---------IQE 307
WP_060386420 189 YPQLQVPAVRFLEDEQPDPYQTAIFLF-HKTELSDMLETLSMSIEKERPVWGYHHIAGATAEEKINTLwhtfpheefLEA 267 Bacteroides ste...
WP_094997437 234 SKWIEKSVSLGQLKFNVESYQIYYFDYgKKLKVRENEHAKRLQKEREEEVKNKERRRKVVAEEKTNSI---------IDD 304 Maribacter coba...

OFY17739     308 IKILRERKSQYFGDVILFLSELNEFEKDVFNSMLNIKSNLKSKTPALNQWIKTATQEDIAFIDFVLNCNEIDIDVNERDF 387
WP_060386420 268 LFYLADHKSSSSILNLLIKEEANEIRDAIHAPNTLHKLQTGLEVGRIYHPEFLLLLWELGYRHKKAEDWQKDNSLTNTTK 347 Bacteroides ste...
WP_094997437 305 LRFLWKNKGYNFSSIEEQMENLDEFELSILNKSDAFKP--KDGQPRIHHWFSIAKKGHIGFLEHMIDSSYLEIDLNEKSK 382 Maribacter coba...

OFY17739     388 EGKTAFQEIYLNK-SI-GKYLPIKGLLKRgyqlitedealavsipdlsgennndlilyklcmslsdksmidiaykysklL 465
WP_060386420 348 MRLYCLDKLFDNTlNIdLKEILTSSIIQA--------------------------------------------------V 377 Bacteroides ste...
WP_094997437 383 DDKTLLATMFENI-AIeHKMWLLKRLIRKgynlkkedeailaqietdpieyestlivfhlanelngcylidelfehkplV 461 Maribacter coba...

OFY17739     466 FIIESAKHATIM-----GFSYKPNEWIAFANNAIQHYskhWEYIEIAFKSS-----------------GlwkilIQLDGK 523
WP_060386420 378 CLIEDIRNNRITftnhpNWKSRINSIRSASNHPLNNY---WGYIDMALDNFhtkegqsmrtylcqkepG-----IKLDNK 449 Bacteroides ste...
WP_094997437 462 CIIESAKRDKII-----GYRYQKTQWIAFANNAIHSYadyWSYIEKAFKNY-----------------GiweklMLLDKK 519 Maribacter coba...

OFY17739     524 GTFKKKITQFYLdmpeqeydfegVFRDLYPELAF 557
WP_060386420 450 EETIVKETNLYK-----------ALTILYPDIYN 472 Bacteroides stercoris
WP_094997437 520 KTFQKKLAKFHAtnpkqkadcllLLNTLYPELKH 553 Maribacter cobaltidurans
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