Conserved Protein Domain Family
DUF6002
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pfam19465: DUF6002 
Family of unknown function (DUF6002)
This entry represents a member of a biosynthetic gene cluster (BGC). This BGC (BGC0000833) is described by MIBiG as an example of the following biosynthetic classes, saccharide and other (unspecified). This family includes a protein from the coumermycin A1 biosynthetic gene cluster from Streptomyces rishiriensis.
Links
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Statistics
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PSSM-Id: 498050
Aligned: 15 rows
Threshold Bit Score: 666.722
Created: 20-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
SBT43929       9 TSRNLISDYYDLIPAAVARCAPPPTGASGtpsFAPAFDLPALTDNVRDFFAAATAGWRRLGEYGGHPIQFLDLTGNPGTR 88 
WP_095565802  10 TLDAALTHYHPRIQDALHRIRAQTPPAPG---FNPGYELPAPDERLNEFFAPSALRVAELGGYGSARLRLLDLMANPATR 86  Plantactinospor...
WP_087929608   8 VLDNALTHYYDRVQTALHRVAESRRADARk-dFSPGPLLTPPTDRFRAYVSVSGLAATEAGEHHGVRLTLLDLMRNPGTR 86  Streptomyces al...
WP_107074871   7 TTRNLITDYYDVIASAVDQCGAVPGGPAGtpgFAPGFDLPELTPAVREYYAAATASWSPLGEYGGHNLQLLDLTANPGTQ 86  Micromonospora ...
WP_106585732  20 SSESLITRYYQGIQLASAELEKKRTgn----gFCPPFEYPDLTDDWEQYFSPAGASWEHLDDYGGKRVVLLDLMKNPEVR 95  Murinocardiopsi...
WP_076971855  10 VVENSLIRYRSQVQSALVRLGDADAGAGPapgFCPGHLLPDPDERLVEFFSPSGLAFHDLGSYQGKRLTLLDLMRNPRTR 89  Streptomyces sp...
WP_067438922  13 QFDAPYAEYAERLRRAMKTVAASRAPQDR---FEPGYELPSPDSRLQRFFAAAAIRVSDLGSYRGRQLRLLDLMSNPATR 89  Streptomyces li...
WP_017618943   8 TTQNAIIDNYEFLEAALRRVGSKKSGPLDt-aFFPEFKVPRMDARLAEFFGAADVSVTRLGSYRGKDVTFLNLMRNPRTR 86  Nocardiopsis gilva
WP_108153671  16 AVVPALSRYWETVGRAVRAMHEHRSLPGD---FTPGAELPPLDGPVRRYLEASEAAVARLPDYRETRMRLLDLRRNPGTR 92  Streptomyces lu...
WP_125642830   2 LLDNALVQYYEEIRAALRDLLGDQERQDTg-gFTPGVELPDLTPAVRAFLSASGLAHAEMPSYRGRRLALLDLARNPATM 80  Streptomyces sp...

SBT43929      89 TTKTFASLVMVARAVEHIRRTGEAIRIFTPTSANKGIALRDAVGRAIEAGLVEPDQLSVVVLAPAATRHKFRQDRLAGDP 168
WP_095565802  87 TTKTIASLVMVARAAQYIRRTGESILIVTPTSANKGTALRDAVFRAIDCGLVPADRLQIVTVAPRSSRHKLWCSGLDRDP 166 Plantactinospor...
WP_087929608  87 TTKTMASLVIVARAAHHVRETGERLMLLTPSSANKATALRDAVLRAVDHGLVTRDGLRVACVVPEESAHKVWRSRLSDDP 166 Streptomyces al...
WP_107074871  87 TTKTFASMVIVARAVEYIRRTGTRLCIFTPTSGNKGVALRDAVARTYAAGLVTPEQLSIVVLAPQSTRHKFRHDALAADP 166 Micromonospora ...
WP_106585732  96 TTKTTASLLMVARAVHHIRRTGESILIFCPSSGNKAVALRDAVARAIDLGLAAPDELRIATFTPARTTYKFRRNLLTESE 175 Murinocardiopsi...
WP_076971855  90 TTKTYPSLVIVARAVRHIMATGERVVIVTPSSANKATALRDAVWRASSSGLVAPGMLRICAVVPDSSRAKLWSSPLSEDP 169 Streptomyces sp...
WP_067438922  90 TTKTLASLLMVARAVQHIRTTAEPVMIVTPSSANKATALRDAVARAIDCGLVTPDELQITVIVPAAARRKLWASPLSGSP 169 Streptomyces li...
WP_017618943  87 TTWTLPSHVMVARAIRHIWSTGEPITLLTPSSANKGTALRDAVLRAIECGLVSADDLQMVTLIPESARDKLWSSSLNEDS 166 Nocardiopsis gilva
WP_108153671  93 TTKTFGSLLMVARAVAYIRRTGEPVTLLTPSSGNKATALRDAVLRAHRAGLADRDQLRIVSVVPERSRAKLWDSPLSSDP 172 Streptomyces lu...
WP_125642830  81 TTKTFASLVIVARAVRFIQDTGQRVTIVTPSSANKAIALRDAVLRALRAGLVDADQLNVVVVVPEGSVAKLRTSELFTDP 160 Streptomyces sp...

SBT43929     169 ALRAANPLLRYVGGAPEDVKALGRAFVDKYAAEAYDRhGVNLWYSLDLRNYLVADAARAAFEADVSP-PSAERPRWHAHS 247
WP_095565802 167 TLARRNPIALYGGDDAAGVKRIAAQFVAGHPGGPAAR-RPHVWYSLDINNYRVADAVRAFFELDFLP-PEPGVRRTHAHS 244 Plantactinospor...
WP_087929608 167 ELRRRNPVLVHAGSG-AAVKALAGEAAGDAAARIRHLtGVRVWHTLDLDNYRAADTVRAYFEDEYLP-PRDGRVRWHSHA 244 Streptomyces al...
WP_107074871 167 RSRQVNPLLRYTGSDPEGVKALGRAFVDEYAATMQDKhGVTLWYTLDLKNYLVADAARAAFEADVAP-ASAARPRWHAHA 245 Micromonospora ...
WP_106585732 176 ELRRLNPILVLDGPQPAAVKELGQEFVRA--AQFGGPrTCRVWYTLDIANYKVADACRAFFEYEFGGaDPAHRRRLHAHA 253 Murinocardiopsi...
WP_076971855 170 WLAARNPVFTYAGAHPDEVKAVARGFVDGWAETFKKRhGVNLWHTLDIENYKVADVIRAHAEYEFLP-RESADERLHVHA 248 Streptomyces sp...
WP_067438922 170 ELARRNPVLTHDGSERSAVKELAQEFTDGWYASPPQGvRHRLWYTLDLDNYRVADTIRAFVEHDALP-APLPGGRLHAHA 248 Streptomyces li...
WP_017618943 167 GLRARNPVAIYSGDEPSNVKKIAREFVDQYGKEFTARtGRRLWYTLDIDNYRAVDALRAAVERRLAP---TAGRRIHVHA 243 Nocardiopsis gilva
WP_108153671 173 ELRRRNPVVTYPGPDPAGVKELARAYYDEYGDLLRTRyGSALWYTLDIANYQAADTVRALMEAELMP-PPPAHGRVHAHA 251 Streptomyces lu...
WP_125642830 161 GLRARNPVAVYGGPVPGTVKSLALQLVDQFRDVLEKAgETNLWYTLQLENYLAADVVRALAEAERFP-AAPGEARLHVHA 239 Streptomyces sp...

SBT43929     248 VSSAYGLLGYNLGRDVLeaa--grARSTDRPGFLLVQHLGTPDMVLNLRY-GGFSRAKMPAYRLDPVRGVTVQDADPRFP 324
WP_095565802 245 VSSAYGLLGHHFGRQLL-------GAPQPAPAYFLVQHLGTPDMVLHLRH-GRVDPADRPGYEQDAGTGLFRQRHDPRFP 316 Plantactinospor...
WP_087929608 245 VSSAFGLLGHHLGTRLLarekigsGAARPSPGYLLVQHLATPDMVLGLHR-DG----GLPAYGLDRGSGLFTQAANPRFP 319 Streptomyces al...
WP_107074871 246 VSSAFGLLGYNLGRDVLeaa--gqASTADRPGFLLVQHLGTPDMVLNLRH-GSFERNNCPAYTLDEGVGAWTQDKDPHFP 322 Micromonospora ...
WP_106585732 254 VSSAYGLLGYQHGLGVLar----lGLPIAQPGFLLVQHLATSDMVAHHLS-GGAGFEMDIDYQPDPETGLLRQQASPHFP 328 Murinocardiopsi...
WP_076971855 249 VSSAFGLLGHNLGLRQLad----gGVNAPRSRYFLVQHLDTPDMVLSLYH-GSPDRDHAPAYTYDAADGLHRQHEDPRFP 323 Streptomyces sp...
WP_067438922 249 VSSAYGLLGHHFGHQMLre----eGLADDPPHYFLVQHLDTPDMVLSLHF-GSVSRENLPEYSRAP-GGLLTQSADPRFP 322 Streptomyces li...
WP_017618943 244 VSSAYGLLGHHFGRSLLsgt--ggEAGDPPPSYFLVQHLGRPEMVLNLYH-GDFSNEHVPDYRLDGEAGLYRQDQEAHFP 320 Nocardiopsis gilva
WP_108153671 252 VSSAFGLLGHHYGTSLTg-----gGEERMPPRYFLVQHLSTPDMVLDLLH-GDASRERMPRFTLETSTGLYHQSSDPHFP 325 Streptomyces lu...
WP_125642830 240 VSSAYGLLGHAYGRSRLpa---dvRSRTTPPHYLLVQHLGAPDMVLSLYNdGSTDTAALPAYDLDPASGMFRQESDPRYP 316 Streptomyces sp...

SBT43929     325 AVTDDPAEVLDPTFYTHEPATSPAMNELIRRFGGDGIVVSRRECLERYPMLRDWFDGDRPMLPTDPDELREWSIVMGLTG 404
WP_095565802 317 AVTYDPAEELDPTFYTHNPPTSPQMDAVIAAQGGDGIVVSLHECMQRYPWIRHRLADAGVALPADPRRLREWSLVMALTG 396 Plantactinospor...
WP_087929608 320 AAADDPSESIDPTFYTKTPATAPAMSEIVRTQGGGGLVVSRHECLARYARVRALVAPAGIQLPSDPARLREWSLVMVVTG 399 Streptomyces al...
WP_107074871 323 AVTDDPAEVLDPTFYTHRPVTSPAMNALIERHGGDGIVVSRRECAQRYPVARDWLANAGLNLPADPEQLREWSIVMALTG 402 Micromonospora ...
WP_106585732 329 YATWSLGEDLEPTFYTKTPVTSPEMTGLIAAHGGTGIVVSLYECLTRYSLARQMLALSGCELPADPRTLAEWSLVMVLTG 408 Murinocardiopsi...
WP_076971855 324 QATADPRERLDPTFYTRRPTTSAEMNEIIRARGGGGIVVSGHECRTLYPRIRRLLAPAGIVLPEDPGLLREWSLVMALTG 403 Streptomyces sp...
WP_067438922 323 QTTKALDECLEPTFYTRAPVTSAEMNRLIRTHGGGGIVVSGHECLTRYREIRRLTARAGLTLPSDPAELREWSLVMAFTG 402 Streptomyces li...
WP_017618943 321 HVADDPEEFLDITFYAYQAATSSDMNDIIAKQGGGGIVVSRRECLDRYNEITKLLAPAGITLPSDPARLRDWSLVMAAAG 400 Nocardiopsis gilva
WP_108153671 326 RTTHHPEEVIDPTFYTRAPMTSRVMTPLIKANGGGGVVVSLHECLARYPQIREMLRPAGVELPHDPRTVREWSLVMVFTG 405 Streptomyces lu...
WP_125642830 317 AQTFDPRETLDPTFYTRNPPTSPRMNELIRTQGGGGIVVSLAECLSRYGQIRAMLGEVGVRLPANPTELREWSLTMAMTG 396 Streptomyces sp...

SBT43929     405 VLNAIDRGLVPaGHEIVLHGSGCYGGSDFVPAEADA--EVSTVDDVAAAVWAKP 456
WP_095565802 397 VCNGLDRGLVQ-ADEVVVHGSGCYGLDDFDPPPAGQirPVRDVDGLAAVIDRAV 449 Plantactinospora sp. KBS50
WP_087929608 400 TLLAVERGLVE-ADEVVVHGSGSYTADDFAPLPAAAlrPVGSVTDVADALHAAA 452 Streptomyces albireticuli
WP_107074871 403 VCNAIDRGLVPaGHDIVVHGTGSYA-NDFAVAVADA--EVSTVADIVAAVLSKW 453 Micromonospora sp. MH33
WP_106585732 409 MTNAADRALIDqFNEVVVHGSGMYPHHSEHAVSRAQtvEVGCLADMLRAVPGTQ 462 Murinocardiopsis flavida
WP_076971855 404 VLQAIDRGLVA-EDDILVHGSGSYHAGDFRPLPEDRltPVTEVEDLAEKAAWAV 456 Streptomyces sparsogenes
WP_067438922 403 VLYAIDRGLVA-EEDIVVHGSGSYSAADFVPLPMRLqrQVGDADEVRTAVLESL 455 Streptomyces lincolnensis
WP_017618943 401 LLLGVDRRLIDaEDDVLLHGSGSYTQDDFTPIPGHHlhGVDDAQRLRTVVFESA 454 Nocardiopsis gilva
WP_108153671 406 VMEAVDRGLLT-EPEVLVHGSGSYAETDFSPIPAQRlqRAADTAELHPVVSRAM 458 Streptomyces lunaelactis
WP_125642830 397 MLNAVDRGLVS-EPDILVHGSGSYSASDYGHLTVRDlhPVTTAEDLQHVVLDAM 449 Streptomyces sp. WAC06614
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