Conserved Protein Domain Family
KPBB_C
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pfam19292: KPBB_C 
Phosphorylase b kinase C-terminal domain
This entry represents the C-terminal domain found in Phosphorylase b kinase regulatory alpha and beta subunits, which control the catalytic activity of the Phosphorylase kinase catalytic gamma subunit. this domain has been proposed as the second calcineurin B-like (CBL-2) domain containing a gamma subunit-binding site.
Links
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Statistics
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PSSM-Id: 497902
Aligned: 50 rows
Threshold Bit Score: 311.801
Created: 20-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
WP_012348325  859 IEHGISQAEAFDHLLDCSPQALLGRLREVIVSEQEMSRDLVRLQSLHVNTTggaesLVALQFPAsNDp-QLpeVVPGWLA 937  Leptothrix ch...
WP_086486734  822 RKKNLPQDAAFEQLLTFSPYELLQQLKSVLQSYRECREQLLALEALHPQNPelcgdLHWVTFPA--D--QT--LNMDWHH 895  Thioflexithri...
WP_002710230  829 PATRLSISQAMDELMNMAPHRVARAVRDVLEHYQDAHDSLTQLERMHVASDsg--gMVTVQFDSsMNp-ELt-YSADWHE 904  Thiothrix nivea
WP_065089452  830 SAGQPAISDTLDVLMDMEPHEFAGALRDVLQHYHAAQDAMQQLERMHVSVDss--gMTRVRFDAgIDp-DNs-DAGDWHQ 905  Acidihalobact...
OQK18180      835 RQQKCNLGEAFDALVALPPHTIELKVKETLADYQNSESQLNMSESLRYEGQik--nLDSARFSEqIDpkDRg-RAGDWHE 911 
WP_023493618  836 GDLHYTNDQAFNEIMSLSPYELSKKVHQTIVDYSNSEIKTGFLEKLNYVGDfl--gLNKAIFAKaAMptDFe-RFENWYQ 912  Methyloglobul...
WP_088619443  837 RETGGTLDQAFNDILFLSPYQLSQKVRETLADYSNTESQLSQVEALNHEGDca--dLGQARFSKaMDaqDHv-GNADWYD 913  Methylovulum ...
WP_064022798  832 RVHSSSLDQAFNDILSLPPHQVATLAQETLEDYNNSENQLGQVETLNYEGPqr--dLAAARFPEtMDpkDRa-GAEDWYA 908  Methylomonas ...
WP_006892613  837 ESGCGTLDQAFNAILSLPPYQLSGNVKETLEDYSNTEDQLGLAETLHYEGDcr--eLTGARFPKnMDpkDHs-EIDDWYG 913  Methylobacter...
WP_336469741  847 ESDCGAPDLTFNEILSLPPYQLFRKVTETLEDYSNTEDQLELSEALHYEGDcr--eLTRARFSKnMDanDRg-DVDGWYA 923  Crenothrix po...

WP_012348325  938 WRELSGAVARVPVDFHERIWALLRQVPGLVIGDQLDARNRLDSAlARADSTPGERGFALQIEDLLNKIHAPEYRQLTIEA 1017 Leptothrix ch...
WP_086486734  896 WRETDGTAGRLTDKFYAALRLLLQRFKGVIIGDKLDSFNRLDSDsIHAEMTSEEKNFILRVEHLLNKIQAPEYRHLVIEA 975  Thioflexithri...
WP_002710230  905 WRSNQGKLGRYSDSFFEGVWDIVNQTHGLVIGDQWNTKLRLAHR-LCADMTRGEKLFRDRVTHILHKTPAPDSLKLYGEA 983  Thiothrix nivea
WP_065089452  906 WRAIQGSLGLYPEDYFEGVWDIVNQSRGLVIGDQWNPKRRLDHK-LCADMTRGERQFQDRVEHILNKTPAPDARQLYTEA 984  Acidihalobact...
OQK18180      912 WREQQGSIGRQTESFFADVWEVLHHCKGLIISEKLNKQRRLDSEhILAEMTDKEKSFVLLINHRLDKVQSPDYRQLTVET 991 
WP_023493618  913 WREMRGSIGKENDSFFAHVWDLLHRCKGVVIGDRLNSKRRLDSEiVLAHMTAGEQSFKLHVNHLLNKIQLPVHRQLTVEV 992  Methyloglobul...
WP_088619443  914 WRERQGSVGRENDAFFASVWTILHHCSGLMIGEKLNSKRRLDSEiILSQMTSGEQSFKIHVSHLLNKIQSPVYRQLTVEA 993  Methylovulum ...
WP_064022798  909 WREQQGSVGRENEAFFSGLWSLLHHCKGLMVGEKYNSKRRIDSEmMLAQMTAGEQTFRLHINHILNKIQAPVYRQLSVEA 988  Methylomonas ...
WP_006892613  914 WREQQGSVGRENDVFFASVWDILHHCKGLAIGDKLNSKNRLDSEnTLSQSTAGEQSFKLHVNHLLNKIQAPVYRQLTVEA 993  Methylobacter...
WP_336469741  924 WREQQGSVGRENSVFFASVWDILHHCQGLTIGEKFNAKNRLDSEtTLSQSTAGEQSFQLHVSHLLNKIQAPVYRQLTVET 1003 Crenothrix po...

WP_012348325 1018 LLALSDIFRANADLQLD-SWLVMDVLVGIAVRLGWEQSLGAEAaaaADYNEHRGQAWKDFYASPPHRVANLVMAAIGFLV 1096 Leptothrix ch...
WP_086486734  976 ILALAEILKKNPDLNTTgDYLVFDVLIGHAVRLAWLSQSPQDR---DNYEQKRSVAWQAFYQLPPHQVANFMMQAFEFLL 1052 Thioflexithri...
WP_002710230  984 LQVLMLVMRNNPQLRIE-DTVYLDVLIGHAVRLAWLQRQPQAA---EDYDQYRADAWKAFYLSPPSDVANHIMTALVYLL 1059 Thiothrix nivea
WP_065089452  985 LRVLMLVMWKNPGLRID-DTLYLDVIIGHAVRLAWEQAHPDQQ---SLYDEQRATAWKDFYLSPPSAVANHVMDALAFLL 1060 Acidihalobact...
OQK18180      992 LHALASIFRDNPDLQVE-DTLMTDTLIYHAVRLTWLDKHPERE---AQYELDHALSWQGFYQLPPHEVANGIIDGLKYLL 1067
WP_023493618  993 LTVIATVFHDNPTLRID-DTLSTDSLIEHAAKIASQKWHRNAQ---KNDEQDEESVWHYFYHLPPHKVANCYVEALTHLL 1068 Methyloglobul...
WP_088619443  994 IKAIASIFHTNSVYIND--TLVTDVIIGHAVRICWLQAHPLHQ---DHYEEHVSIAWQAFYQLPPHRVANGILDALVHLL 1068 Methylovulum ...
WP_064022798  989 LRALASIVKENPDLYID-DTLVTDILIGHAVRISWLQRHPQYR---DHYEECVSLAWQAFYQLPPHGVANAILDALIHLL 1064 Methylomonas ...
WP_006892613  994 LKAMASIFRETPSLHID-DTLLTDIIIGHAVRVSWLQAHPESK---DNYEECVSLAWQDFYRLPPHKVANGILDALIYLL 1069 Methylobacter...
WP_336469741 1004 LKAIAFIFRENPALHID-DTLVTDTLIDHAVRINWLQSNPEHK---DNIDDSTLLAWQDFYHAPPHQIANGILDALIHLL 1079 Crenothrix po...

WP_012348325 1097 EQAr-rEE 1103 Leptothrix cholodnii
WP_086486734 1053 TVEk-nAV 1059 Thioflexithrix psekupsensis
WP_002710230 1060 NSDakeAV 1067 Thiothrix nivea
WP_065089452 1061 NGSarqSA 1068 Acidihalobacter prosperus
OQK18180     1068 ATNn-eIP 1074
WP_023493618 1069 DNTp-qDF 1075 Methyloglobulus morosus
WP_088619443 1069 NNNs--LP 1074 Methylovulum psychrotolerans
WP_064022798 1065 NNAn-pTE 1071 Methylomonas sp. DH-1
WP_006892613 1070 NNNe-rAT 1076 Methylobacter tundripaludum
WP_336469741 1080 NNNd-rSS 1086 Crenothrix polyspora
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