Conserved Protein Domain Family
YegS_C
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pfam19279: YegS_C 
YegS C-terminal NAD kinase beta sandwich-like domain
This entry represents the C-terminal domain found in the YegS protein. It is related to the beta sandwich domain of NAD kinases. The structure of YegS reveals a two-domain protein with the active site crevice found between the two domains. The C-terminal domain contains 13 beta-strands and two alpha-helices. The likely substrate for YegS is phosphatidylglycerol.
Links
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Statistics
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PSSM-Id: 497891
Aligned: 35 rows
Threshold Bit Score: 131.185
Created: 20-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
WP_013838693 149 GAVSAGLDAAVTARANAMRRP---RGNARYTLAALAEIATFRAWSYTLELAGVVddgglpltgppgaLTWHGraALVTVA 225 Isoptericola va...
WP_094764834 156 SVVSTGYDARVNKATNDFRFPigpLGPLAYGALALGEVARFTPLDYRIEIDGQP-------------RELSS--VLVAVA 220 Luteococcus jap...
WP_237268220 147 AVVSSGYDARVNRATNDIRLR---FGALSYGYIALRELASFDPLRYRLTIDGVQ-------------HEVSA--MMVAIA 208 Tessaracoccus f...
WP_076058443 147 AVVSSGYDARVNRATNDIRLR---FGALSYGWIALRELASFAPLEYRLVIDGQP-------------RELRA--MMVAVA 208 Tessaracoccus s...
WP_093251562 146 AVVSSGYDARVNRATNETHLR---FGSLSYGAVALRELANFAPMAYRLVIDGEP-------------RELDA--MLVAIC 207 Tessaracoccus o...
WP_077342132 147 AVVSSGYDARVNRATNDIKLR---FGPLSYGYIALRELANFSPIHYRLTIDGEP-------------RELDA--MLVAVC 208 Tessaracoccus f...
WP_094363836 159 TVVATGYDSRVNRRANRMRLP---IGNLRYAASALAELAVFEPLTYRLRIDGRQ-------------RTQPA--MFIAVG 220 Enemella dayhof...
WP_092609149 158 SIVSTGFDALVNLRANHTTFP---RGRLRYAWSATVQLARFEPLPYRLVIDGEA-------------REFPA--ILVAVG 219 Raineyella anta...
WP_231946364 152 SVVASGFDARVNRRANAMSRP---KGSLRYAVAALAELATFTPLSYRLSLDGRP-------------RELDA--MLVAVG 213 Auraticoccus mo...
WP_041976540 161 ATIGFGAEVAARVAAQDGLFRf-lPGEARFTLAALSALKGWREQPVRIRVDDDL-------------FESRS--NLIAIT 224 Pyrinomonas met...

WP_013838693 226 NTPRIGGGIRVAPDASPTDGLLDVVVATVRTRATAAALFPTMYAGRHVHHPDVHVVRARSVTVRpg---pdAARpgeppL 302 Isoptericola va...
WP_094764834 221 NAGHFGGGMKIVPQADVTDGLLDVLLVGDLKRRQVLELLPKLYRGAHVGHPAVEFVRARTVRIDgeavgrdGSRs----P 296 Luteococcus jap...
WP_237268220 209 NTGIFGGGMRIAPDADPTDGLLDVTIIHEASRTKLLRLLPSVYSGKFVTNPVVERLRAKVVEFD-------GDD------ 275 Tessaracoccus f...
WP_076058443 209 NTAVFGGGMQIAPDADVADGLLDVTIIHEASRGKLLRLLPSVYTGGFVTDPVVERLRAQTVEVD-------GDG------ 275 Tessaracoccus s...
WP_093251562 208 NTGVVGGGMLISPDADFADGLLDLTIVHPVGRGKLLRLLPSVYTGKFVSDPAVERFTAASVAVD-------GDD------ 274 Tessaracoccus o...
WP_077342132 209 NTGVFGGGMQISPDADPSDGLLDVTIIHEASRGKLMRLLPLTYTGSFVKDSAVERFRAARVEVD-------GDG------ 275 Tessaracoccus f...
WP_094363836 221 NGAYFGGGMKICPDADVTDGLLDVTVIHPVSRATLLRLLPAMFSGSFVRDPAVERFRARVVEVD-------GDG------ 287 Enemella dayhof...
WP_092609149 220 NAGYAGGGMAMCPSADVTDGLLDLTIVHPVSRATFLRLLPSLFNGTFVRDPAVEQLRAREVRVD-------GEG------ 286 Raineyella anta...
WP_231946364 214 NGGFFGGGMNICPDADPRDGLLDVTIVHPVSRPTLLAMLPLMFGGSFVRHPAIERTRASRVEVL-------GED------ 280 Auraticoccus mo...
WP_041976540 225 SGPYAGGGIMLAPTARADDGLLDVVVAAGVTKMTVLRELPRARDGKHLRNPRVRLLRGKTVYIEp-----lASEa----P 295 Pyrinomonas met...

WP_013838693 303 PPAHADGEHLGAPPLRAEAVPGALRLLA 330 Isoptericola variabilis
WP_094764834 297 MFAMGDGESLGGVPLNATVRPGLIAVFR 324 Luteococcus japonicus
WP_237268220 276 LFVTGDGEEMGEVPARVEAVPGILNLIV 303 Tessaracoccus flavescens
WP_076058443 276 LFLMGDGEEMGDVPATVTCVPGCLKVIV 303 Tessaracoccus sp. ZS01
WP_093251562 275 MFLMGDGEELGDVPATVECDPGALRVYT 302 Tessaracoccus oleiagri
WP_077342132 276 LFAMGDGEEIGDVPVTVECAPSALRVIV 303 Tessaracoccus flavus
WP_094363836 288 LFGMGDGEELGPTPLRISVEPSSLTVFG 315 Enemella dayhoffiae
WP_092609149 287 LYGMADGEELGPVPLVIEVEPQALTIFT 314 Raineyella antarctica
WP_231946364 281 LVAMGDGEPLGPTPLVVESVPGALTLLG 308 Auraticoccus monumenti
WP_041976540 296 LQLEADGEVRGAIPARFQIVPQALRLAF 323 Pyrinomonas methylaliphatogenes
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