Conserved Protein Domain Family
CoV_S1_C
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pfam19209: CoV_S1_C (This model is not part of the current CDD release)
Coronavirus spike glycoprotein S1, C-terminal
This entry represents a domain found at the C-terminus of the Coronavirus S1 protein. It is found across a range of alpha, beta and gamma coronaviruses. This small all beta stranded domain is known as subdomain 2 in the structure of the porcine epidemic diarrhea virus spike protein.
Links
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Statistics
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PSSM-Id: 523577
Aligned: 24 rows
Threshold Bit Score: 59.9417
Created: 20-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
YP_009113025  624 GVCVKYDLYGISGQGIFTE-VNATYYNSwqnLLY-DSNGGLYGFKdFLTNRTYMIRSCYSGR 683 
YP_009389425  429 NKCNVWTFNDITFEGVLLE-TNKTFNPQlkaLYK----GSMVVMI-RVFGIVYEVVPCIKTR 484 
YP_009336484  428 DVCKSYTIDGVTFQGILRN-TTHQIDSFhniLYY----GDMVSYV-RIRGVVYAVESCNRFY 483 
YP_009072440  582 NECITYHIYGYKGTGVIVS-ANYTFQSFq--TVQlTSTGSLHSFK--YNNTIYGILPCAQAQ 638 
YP_009513010  588 GQCIDYDIHGVVGRGVFQVcNTTGIASQ---IFVyDGFGNIIGFH-SKNGTYYCMAPCVSVP 645 
A3EXG6        528 DRCVQYNLYGYTGTGVLSKnTSLVIPDGk--VFTaSSTGTIIGVS--INSTTYSIMPCVTVP 585  Rousettus bat coronavirus HKU9
4_pfamImport    1 DQCVTYNVYGYTGTGVFTT-SNLTIPDNk--LFSaSATGAISAVS--IHNAVYAISPCVSVP 57  
YP_009273005  540 GQCVKYNFYGYAGTGVINQ-SDLAIPNNk--LFVtSKSGAVLAVR--AGDKVYSITPCVSVP 596 
YP_005352863  480 NECVDYNIYGKTGTGIIQS-TNVTLLAG---RTYtSASGQLLAFKyLSNQTIYSVTPCDFSN 537 
YP_009201730  613 NVCTEYNIYGIVGKGIINK-ANSTLHTG---IVYtDTAGVLVSFKnVTTGDIYSVIPCQTSM 670
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