Conserved Protein Domain Family
acVLRF1
?
pfam18859: acVLRF1 
Actinobacteria/chloroflexi VLRF1 release factor
Archaeo-eukaryotic release factor domain family belonging to the VLRF1 clade, observed primarily in the actinbacteria and chloroflexi bacterial lineages. Contains a conserved glutamine residue in the release factor catalytic loop, suggesting it functions as an active peptidyl-tRNA hydrolase at the ribosome.
Links
?
Statistics
?
PSSM-Id: 497584
Aligned: 93 rows
Threshold Bit Score: 64.5178
Created: 20-Feb-2025
Updated: 28-Apr-2025
Structure
?
Aligned Rows:
Download Cn3D
PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
WP_066635324  77 PPLLVMLVRRGG-YA--VALVSaDGDLVAHKVGTRHVQSRTAAGGWSQQRYARRRGHQADALVEAVVGHAA-RLLapp-- 150 Serinicoccus hy...
WP_015300039 178 GPHLLALVRADR-FA--IGRYD-GTERVEYAGFESDVKGAHSKGGFSQARFERIRDEQIDDHVAQARAAIE-DVR----- 247 Halovivax ruber
4_pfamImport   1 DRHALALVRTDL-FA--VGVYD-GDERLEVHGFESEVKGSHSKGGFSQARFERIRDEQIDDHLERATAALEeRVA----- 71 
WP_013879189 184 GRYALAVVRTDL-FA--LGIYE-DGERVDYRGFESDVKGSHSKGGFSQARFERLRNEQIDEHLDECRETLE-EYV----- 253 Halopiger xanad...
WP_054863012 184 GRYAIALVRTDL-FA--LGIYH-GNERLEYHGFESDVKGSHSKGGFSQARFERIRNEQIDTHLDRCDEALA-KHIgsrle 258 Natronolimnobiu...
WP_018382930 118 RLLVAHVDRRGArFE--LRTSL-GHEPLGESRGERFPVHRTGRADWSSKHYDYKVEDRWDRTARTVAERVN-ELC----- 188 Wenjunlia vitam...
WP_017883807 118 RYLVVETGREGA-DVraESADRsAPQHVVEVEGRDDSLPKVQAGGWSHARYQRHSEEIWKHNQSEVAEVVD-RLV----- 190 Leucobacter sp....
SMC53803     118 PHVVVVADSSGA--D--LHSFDgQVELVQSVRGRQHPLHKAGGGGWSHRRMHQRVEDTVKHNAKQVADEVE-RLV----- 187
WP_093262857 117 PHLRVIADHTGA-DV--ITVGA-DVPRQRTVQVEEWPMQKTGVGGWSQRRYERGVEETWERNAVAVAEAVD-REV----- 186 Thermostaphylos...
WP_091093816 105 PHLRVIVDHAGA--E--LTVYGsGAPRKRTVAATTWPLQKTAQGGWSQRRYEVSVENAWEQNAQAVAHEID-EQV----- 174 Nonomuraea wenc...

WP_066635324 151 ---------apsP----PDSSDrphglrrpaarfastdrtvcaadlggVVLGGDRSLAAEVMSG-LL--DGPalpgdvrs 214 Serinicoccus hy...
WP_015300039 248 -----------------DEAADl------------------------pLYLAGQRDVLDELADQ-LD--PGP-------- 275 Halovivax ruber
4_pfamImport  72 -----------------GEVDR--------------------------LYLAGQRGVVDTLAEE-TSidPAP-------- 99 
WP_013879189 254 ------------GaqaqSGRAAvd-----------------------rLFLVGQRGVVDTLVDE-SGpeLEP-------- 289 Halopiger xanad...
WP_054863012 259 qadgggrqtstvAngagAGGGDdens------------------gierLFLVGQRGVVDTLADE-ID--LEP-------- 309 Natronolimnobiu...
WP_018382930 189 ------------G----EADADl-------------------------VVLAGDPRERRAVHDR-----LDE-------- 214 Wenjunlia vitam...
WP_017883807 191 ------------R----EERPVv-------------------------VVLAGDLRARQLLRER-----LAPa------- 217 Leucobacter sp....
SMC53803     188 ------------D----EVRAEl-------------------------VVLGGEVQARSAVRTE-----LGL-------- 213
WP_093262857 187 -----------------RRTGAe------------------------lVVVAGDPRSRALVRDHlGA--ASAdravmaeh 223 Thermostaphylos...
WP_091093816 175 -----------------RRLGTe------------------------lIIVAGEPKSRSYLMHH-------Lgtkatdrv 206 Nonomuraea wenc...

WP_066635324 215 aLSGLPRR----ELW-D-----LPDPRRAVLDDAVRRGRAVQVE 248 Serinicoccus hydrothermalis
WP_015300039 276 -DALAAVD--------A-----TGDT-ERALDDAHRSFWSTELL 304 Halovivax ruber
4_pfamImport 100 -AATAAVD--------A-----TGNP-ESALEDAYRSFWTTELQ 128
WP_013879189 290 -DATAAVD--------A-----TGDP-KPALEDAHHSFWTTELH 318 Halopiger xanaduensis
WP_054863012 310 -AATAAVD--------A-----TGDP-KPALEDAVHSFWTTELH 338 Natronolimnobius baerhuensis
WP_018382930 215 -LLPDALE--------T-----GPEPRPEELDDLRRHWRQSRLA 244 Wenjunlia vitaminophila
WP_017883807 218 -SRELVVEv---EAHtR-----AAGSDERVLDDAIADALTERTH 252 Leucobacter sp. UCD-THU
SMC53803     214 -DDDLVVEvegtGLAgGtdddeFGNAVRALVAQRQQRRDADVVE 256
WP_093262857 224 gSRGAGAA----AA--P-----FEADAEAAVDSWLERRRTELIE 256 Thermostaphylospora chromogena
WP_091093816 207 vMVEHGSR----SDHgQ-----FEEDVEQALDDWLDRRRAELLE 241 Nonomuraea wenchangensis
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap