Conserved Protein Domain Family
KfrB

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pfam18790: KfrB (This model is not part of the current CDD release)
KfrB Domain
This is a domain found in polyvalent proteins of conjugative element or often in the neighbourhood of one. The KfrB domain has been speculated to play a role in discrimination of self from non-self in plasmid conjugation systems. This domain has been described as having an OB-fold. Additionally in some proteins it has a four stranded beta sheet elaboration to the N-terminus that packs against the side of the OB barrel that is not included in this entry. The KfrB domain is also found at the C-terminus of some zeta toxin proteins.
Statistics
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PSSM-Id: 523448
Aligned: 96 rows
Threshold Bit Score: 33.3147
Created: 20-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_066978095   68 SYYGPVILNNDNY--LVQAV---GKdrL-FAI-VHEKQniAFQgaaLPtldakksLNGTNIQIHYt-nDKAKAYP 134 Methylomonas lenta
WP_152617348  312 GYSGRVLAINDRY--VLQHS---GK--D-HVT-LHRAR--SFE---ELp------AAGQNARISYk-qGKAQVNE 365 Paraburkholderia sa...
WP_012777711  290 AHYGKIIAVSERY--ILQHG---GQ--N-EFK-LHRKS--SLG---QTv------SENQNLKITYd-kGRGSVED 343 Methylovorus glucos...
10_pfamImport   1 NHSGEIINVNGRF---AAQLtgfGNenGaAFVsIHRLA--NLN----Ep-----vYKGDDVRISYnnnGIGTVYD 61 
6_pfamImport    1 ALRGEIISVNDRY---AAQLtgnGRrdGvAFVtLHRLA--DLS---EAv------LKGDKVSITYdekGRAKVGQ 61 
WP_012777710  149 NYYGSIIGVSKRF--ALQNT---GQ--G-TLI-AHDLN--LID---GSv------QVDQKYKIKYg-nGQGIAEL 202 Methylovorus glucos...
8_pfamImport    1 NHTGKIKSVGKHF--LVQQTkdnGT------V-VHENS--ILN---SDe-----sAVGHDVLINYr-nGVHKISI 55 
WP_106371278  228 EYIGEICYVSSYY--AVQQT---RL----FLV-MHERA--LLN---SAv------EVGQVAQIRYr-eGVGSVEL 280 Chlorogloea sp. CCA...
WP_015556424  207 WFTGKIIHTDAAHgrCIQQT---AS--R-LFT-VHRLE--KLE---TVp------EQGQDLKITYskdGAKAKLD 263 Fretibacterium fast...
WP_015555779  208 TYKGEIIHVNEEQgyCLQRI---GS----GLY-VHRLD--RLD---VSp------ERGQNLKIAYardGSTARVE 263 Fretibacterium fast...
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