?
Alpha-galactosyl-binding fungal lectin This domain can be found in alpha-galactosyl binding Lyophyllum decastes lectin (LDL). It is composed of five-stranded anti-parallel beta-sheet and two alpha-helices and contain conserved cysteines responsible for disulfide bridges. The protein with the highest similarity is ginkbilobin-2, a protein with apparent anti-fungal properties isolated from the seeds of the ginkgo biloba tree. Homologous sequences can be divided into two groups, where the proteins in the group with closest homology to LDL only consist of a single LDL-like domain. In the second group of sequences, the LDL-like domain is found at the C-terminal end of a larger domain with homology to members of the Ser, Gly, Asn, His consensus sequence (SGNH)-hydrolase family, which is part of the Gly, Asp, Ser, Leu motif-esterase/lipase superfamily. |
Jiyao W et al.(2023). "The conserved domain database in 2023.",