6L1W,6UEI


Conserved Protein Domain Family
zf-CCCH_8

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pfam18633: zf-CCCH_8 (This model is not part of the current CDD release)
Zinc-finger antiviral protein (ZAP) zinc finger domain 3
Zinc-finger antiviral protein (ZAP) is a host factor that specifically inhibits the replication of certain viruses, such as HIV-1, by targeting viral mRNA for degradation. N-terminal domain of ZAP is the major functional domain which contains four zinc-finger motifs. This entry represents the third zinc finger type CCCH.
Statistics
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PSSM-Id: 523382
Aligned: 6 rows
Threshold Bit Score: 61.7122
Created: 19-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6L1W_A        144 PFFMPEICKSYKGEGRKQICGQPQPCER 171  house mouse
XP_003503272  143 PFFMPEICKSYKGEGRKQICGQPQPCER 170 
XP_035555846  143 PFFLPEICKNYKGEGRRVICDKYPQCER 170 
XP_069927541  143 PFFLPEICKTYKGEGRKQICSHQPLCER 170 
6UEI_A        145 PFFMPEICKSYKGEGRQQICNQQPPCSR 172  human
XP_056655732  141 PFFLPDICKHYKGENRSDSCSKKTECQR 168  gray short-tailed opossum
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