2C1I


Conserved Protein Domain Family
PgdA_N
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pfam18627: PgdA_N 
Peptidoglycan GlcNAc deacetylase N-terminal domain
This is the N-terminal and middle domain found in Streptococcus pneumoniae peptidoglycan GlcNAc deacetylase (SpPgdA). PgdA protects the Gram-positive bacterial cell wall from host lysozymes by deacetylating peptidoglycan GlcNAc residues. It is a member of the family 4 carbohydrate esterases (CE-4).
Links
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Statistics
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PSSM-Id: 497400
Aligned: 5 rows
Threshold Bit Score: 306.786
Created: 19-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2C1I_A        16 QKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGE-KVISSVRELINQDVKDKLESKDN-------LVFYYTEQEE 87  Streptococcus p...
WP_067102074  34 QVETYLSSRQEELAGDQTVRQEGKVGTTYVTAYIPKNKAnEEIPALKEIILSQVHADLGQTKPkdk-vtdFYYITAQTTS 112 Streptococcus s...
WP_011836827  46 EKVSVLISQEETFHAEKTEKQSKMIGSHYVEAFYPLLDG-QVMASVKEQMDADSQTIKDNQKKgdk-ieeLTFYYAEEKE 123 Streptococcus s...
Q8DP63        48 QKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGE-KVISSVRELINQDVKDKLESKDN-------LVFYYTEQEE 119 Streptococcus p...
WP_067192243  41 KLHHAIQDGKTLTIAQNSTEHAGWIGDKYVTAYYPRMGT-TEYEVVKSRIDAETMALQVAQPEladelreIIFYGSEEGS 119 Streptococcus s...

2C1I_A        88 SGLKGVVNRNVTKQIYDLVAFKIEETEKTSLGKVHLTEDGQPFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQI 167 Streptococcus p...
WP_067102074 113 SDLKDITAYQLVSVKDQKKGQSIEKGERVTHSPVYFTSNMKRFSFADLFEHTDLAQEVLLTRIQEELNKTSLSDTDKQEK 192 Streptococcus s...
WP_011836827 124 TSLKDVKEVLVHRKDYHVKEMKISKGEEREVADSYLGADGSPFTLDKLFQDPDAAKEIFINEISSQLTFRQADEAVQTEI 203 Streptococcus s...
Q8DP63       120 SGLKGVVNRNVTKQIYDLVAFKIEETEKTSLGKVHLTEDGQPFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQI 199 Streptococcus p...
WP_067192243 120 SELVNLKQVSIQKVLHKIDNRKIGSAEKETISSLYLNADGQEITLANLFINPELAKSSMENFIHQQLIFRGLSEDQVQET 199 Streptococcus s...

2C1I_A       168 VKNFSDQDLSAWNFDYKDSQIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQ 227 Streptococcus pneumoniae R6
WP_067102074 193 LAQAKQLKLADLDFTYKDSQLVISLPEKTVGLATVQIPIGQLFDCIHSQYLTDKDQTSYQ 252 Streptococcus sp. DD13
WP_011836827 204 LNTLNGTELGQWSFRYEYSHFSIKLSKEVQGLTSIDVPLSSFYDQINADYLTGDDLAAYQ 263 Streptococcus sanguinis
Q8DP63       200 VKNFSDQDLSAWNFDYKDSQIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQ 259 Streptococcus pneumoniae R6
WP_067192243 200 IRALESQELSQWQFSYRDATFAIKLPNATAGVLNIDVPLSELYNTIDSTYLQGQDLEKYQ 259 Streptococcus sp. DD10
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