5J67


Conserved Protein Domain Family
ASTN_2_hairpin

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pfam18577: ASTN_2_hairpin (This model is not part of the current CDD release)
Astrotactin-2 C-terminal beta-hairpin domain
This is a beta-hairpin domain found at the C-terminal region of astrotactin 2 proteins (ASTN-2). ASTN-2 is an integral membrane perforin-like protein linked to the planar cell polarity pathway in hair cells. it consists of multiple polypeptide folds: a perforin-like domain, a minimal epidermal growth factor-like module, a fibronectin type III domain Fn (III) and an annexin-like domain as well as the beta hairpin domain which packs across the fibronectin domain.
Statistics
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PSSM-Id: 523350
Aligned: 6 rows
Threshold Bit Score: 86.8175
Created: 19-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5J67_A        519 IQSRVETVPYLFCRSEEVRPAGMVWYSILKDTKITCEEKMVSMARNT 565  human
XP_002935251 1173 IQGRIDTMPYLICRSEDLRTSGFIWYNILKDNKVTCEEKMVPMSRNM 1219
XP_007569675 1321 IQSRTDTMAYIYCRSEEGGLPSM-WHGSLHERRALCMEKLMSLQRNT 1366
KPP67094      167 IRSRTDTVPYVFCRSEEMRPPGSVWHSSLQEVHLSCVEKLMSVPRNT 213 
KPP67218      158 IQGRTDTVPYVACRSEEARPMEALWRSSLHETRLSCVEKLASVRRNT 204 
XP_069039394 1193 IQSRTDTVPYIFCRSEEIRPINMVWHSSLQDTKVTCIEKLMSIPRNT 1239
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