4RXI


Conserved Protein Domain Family
DUF5617
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pfam18493: DUF5617 (This model is not part of the current CDD release)
Domain of unknown function (DUF5617)
This domain of unknown function is found at the C-terminal end of proteins mainly from Legionella, including lpg0944 from Legionella pneumophila, which is thought to be an effector of the Icm/Dot translocation system from this bacteria. This domain folds into an all-alpha structure.
Links
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Statistics
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PSSM-Id: 523308
Aligned: 8 rows
Threshold Bit Score: 121.767
Created: 19-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
4RXI_A        27 FAAYHELWRNAFQEIxndprhqlhrndveykkiHAIRTVLDDYTKGGntwwAKFRRIFTFHWNRHHVKVVDDIVKEI-DA 105 Legionella pneu...
WP_006869803 266 RAFYEKCYEKNRDVL------------------TNARNLLNNYTENN----SMLMRFFSGHWNRHHVAAVNKLVEQI-DK 322 Legionella dran...
1_pfamImport   1 PASYHQLYQTSKDPL------------------QSARALLNDYTKGN----SWWLRFFTGHWNRHHIQEVAQIVKKM-DD 57 
WP_018578134 458 PSSYDRM-SDQTNSL------------------ANARNILNDYTKNN----SLFSRLIHGHWNRHHVKEVHEIVKDI-DA 513 Legionella shak...
Q5ZXT9       416 PDSYKRIWDSADGDSn----------------iTKIKALLKDYTKEDsilgSFWGLIFTLHWGRHHVKSVHQI-----AQ 474 Legionella pneu...
WP_058521254  51 PDTYAKIWNKIKGNSn----------------qRRIKALLIDYTKENclfgSFIGRMISRHWNRHNVRAVSKIIANIsVK 114 Legionella tucs...
WP_058530974  30 PASYYEL--DKDDTL------------------AAARNLLNDYTKSN----SGLGRAFTFHWARHHTAEINQVVEDI-DN 84  Legionella rubr...
Q5ZWY9       256 FAAYHELWRNAFQEImndprhqlhrndveykkiHAIRTVLDDYTKGGntwwAKFRRIFTFHWNRHHVKVVDDIVKEI-DA 334 Legionella pneu...

4RXI_A       106 GNYTTSRALVDRLDNLA--IslgskL---NPKGTLKEQIGFIK 143 Legionella pneumophila subsp. pneumophila str. Phila...
WP_006869803 323 KQITDIADLMKQLKEIK--L-----V---NPNGSLARRICFIE 355 Legionella drancourtii
1_pfamImport  58 GIIKDKHSLLTELNKIH--L-----V---NINGSLARRIQFIE 90 
WP_018578134 514 KNIKNMDELVMRLSAIH--L-----E---NPKGSLARRMEFIV 546 Legionella shakespearei
Q5ZXT9       475 TKYTSVEAILSDLKALK--------P---REGGSLDKRIKFIE 506 Legionella pneumophila subsp. pneumophila str. Phila...
WP_058521254 115 NYYDSADDIVSDLKTLK--------P---EKGGSLYQRIKFIE 146 Legionella tucsonensis
WP_058530974  85 GVIQDMDSLINRLKSIE--L-----V---NPKGSLSRRIDLIV 117 Legionella rubrilucens
Q5ZWY9       335 GNYTTSRALVDRLDNLAisL-----GsklNPKGTLKEQIGFIK 372 Legionella pneumophila subsp. pneumophila str. Phila...
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