3OPY


Conserved Protein Domain Family
Pfk_N
?
pfam18468: Pfk_N 
Phosphofructokinase N-terminal domain yeast
This is a phosphofructokinase (Pfk) N-terminal domain found in yeast ATP-dependent 6-phosphofructokinase subunit alpha. ATP-dependent 6-phosphofructokinases (Pfks, EC 2.7.1.11) catalyze the phosphorylation of fructose 6-phosphate (F-6-P) to fructose 1,6-bisphosphate, a key control step of glycolysis in most organizms. The N-terminal domain contains the active site and is related to glyoxalase I (E.C. 4.4.1.5).
Links
?
Statistics
?
PSSM-Id: 408261
Aligned: 7 rows
Threshold Bit Score: 131.107
Created: 27-Mar-2022
Updated: 17-Oct-2022
Structure
?
Program:
Drawing:
Aligned Rows:
Download Cn3D
PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
3OPY_A         7 SDLSFTSFVTNDDNLFEETFNFYTKLGFHATRSYVKDNRS-DFEL----TGISTDSIKEIWLESFPLSEVveASGGrelr 81  
XP_013936214   5 SSFNFSSFVTTKTQDYVALIQFYKSFGLSVVKTFSKDANTaGTEL----IGVSTDSRKECWFSCFPAADL--AGHG---- 74  
EGV65313       4 EGLSSISLVTDSPDKFTAAAKFYVRAGFTALKSYNKHL-N-KPDL----LGVSSDSIRELWLQSFPVEEV--DSHGqvip 75  
EDK38928       5 NGISSISFVTTDPAELEAACKFYTSLGLRLTRSYPKNTSG-FSSCpeyhLGVSSDSIQEIWFESFPLQDT--DKNGclip 81  
XP_003645817   7 YGVGFTSLTTAEEDKYKATIKFYQELGFSIVKIYDKFKNH-DNGVi--aSGTTHGSRKETWLESFKLSEM--DARGfrvp 81  
Q92448         7 SALSFTSFVTNDDKLFEETFNFYTKLGFHATRSYVKDNRS-DFEL----TGISTDSIKEIWLESFPLSEVveTSAGrelr 81   Komagataella p...
Q6BH76         9 EGISFISLITNKNEEFEESANFYNKLGFRLTKNFSKITNN-SESKpklqIGISNDSLKELWLESFPLQNT--DENGfirp 85   Debaryomyces h...

3OPY_A        82 kplqesVGyeseallgysPYQSGGVVIKLRL 112 
XP_013936214  75 ------PG----------GAFSKGTIIKLRL 89  
EGV65313      76 --fqesAVyqg----dncESLSDPVLIKLRL 100 
EDK38928      82 --wqelPIytg----dksAKLSQSFVIKIRL 106 
XP_003645817  82 --qqeaSN----------PEQSDGILLKIRL 100 
Q92448        82 kplqesVGyqseallgysPYQSDGVVIKLRL 112  Komagataella phaffii GS115
Q6BH76        86 --wqelLVydg----dgcEKLNSATTLKIRL 110  Debaryomyces hansenii
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap