Conserved Protein Domain Family
HetR_C

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pfam18460: HetR_C 
Heterocyst differentiation regulator C-terminal Hood domain
This is the C-terminal hood domain found in Heterocyst differentiation control protein (HetR). HetR-C binds to PatS peptide. Two PatS6 peptides bind to the lateral clefts of HetR-Hood domain, and trigger significant conformational changes of the flap domain, resulting in dissociation of the auxiliary alpha-helix and eventually release of HetR from the DNA major grove and termination of transcription.
Statistics
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PSSM-Id: 497266
Aligned: 5 rows
Threshold Bit Score: 136.931
Created: 19-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_015204066 219 DSEERTYIMIEDTARYFRLMREWAAREPQVIRLLEELDILPEQMDEAIAELDEIIRTWADKYHTSGGQPMVLQMIFGSK 297 Crinalium epipsa...
1_pfamImport   1 DEQERTYIMVEDTARYFRMMKDWAERKGRVMRVLEEMDIPSEEMEVAMSELDEIIRDWADKYHKEGGTHMILQMVFGKK 79 
WP_035158134 219 DDQERQYIMVEDTARYFRMMRDWAERLANTMRVLEELDIPPDNISPALEELDEVIRAWADKYHQDGGIPMILQMVFGKK 297 Calothrix sp. 336/3
Q9AH77       219 DDQERTYIMVEDTARYFRMMKNWAERRRNAMRLLEELDILPEKMEQAMEELDEIIRAWADKYHQDGGIAVVLQTVFGEK 297 Nostoc punctifor...
WP_015200495 219 DEQERTYIMVEDTARYFRMMRDWAERKPKAMRILEELDIPPERLEQAQEELDEIIRAWADRYHQEGGMTVVLQMVFGKK 297 Calothrix sp. PC...
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