1YU2


Conserved Protein Domain Family
Mtd_N

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pfam18454: Mtd_N (This model is not part of the current CDD release)
Major tropism determinant N-terminal domain
This is the N-terminal domain of major tropism determinant (Mtd), a retroelement-encoded receptor-binding protein. Mtd-N forms a three-fold symmetric beta-prism. This resembles the pseudo three-fold-symmetric beta-prisms of monocot lectins, but lacks residues in these lectins identified as binding carbohydrates. The beta-prism and beta-sandwich domains reinforce overall trimeric assembly and therefore may have indirect roles in stabilizing the backbone of the variable region.
Statistics
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PSSM-Id: 523290
Aligned: 26 rows
Threshold Bit Score: 46.8485
Created: 19-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1YU2_A         5 VQFRGGTTAQH--ATFTGAAREITVDTDKNTVVVHDGAT 41  Bordetella phage BMP-1
1_pfamImport   1 IIVRNDTEANWvsANPVLLKGEAGYSTDKLYLKFGDGST 39 
WP_056756762   4 IRLRRGTTAQWqaANPVLLQGEPGVDTTTGALRIGNGTS 42  Nocardioides sp. Root190
EEF25823       9 VRWRRGTAAQH--ASFTGALAEVTVNTDKKALHVHDGST 45 
WP_066133950   5 LQLRGGTAGEH--ETFTGKVREVTVNTTRGTLHVHDGQT 41  Bordetella ansorpii
WP_066133951   6 LQFRGGTTAQH--ATFVGAQRELTVDITKKVVVVHDGVT 42  Bordetella ansorpii
Q775D6         5 VQFRGGTTAQH--ATFTGAAREITVDTDKNTVVVHDGAT 41  Bordetella phage BPP-1
WP_012592038   5 VKSRRETASFL--STYVGATGELLVDTTSWRVQVHDGAT 41  Methylocella silvestris
WP_012385646   5 VQLRRGSETDI--ASFKGAQGEIVMDTTNNRLILCDGTT 41  Beijerinckia indica
WP_008088258  10 IQHRGMSTQEWesSSDILREREIGIDMTTGYPKVGDGKS 48  Streptococcus ictaluri
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