2KFS


Conserved Protein Domain Family
Rv2175c_C
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pfam18367: Rv2175c_C (This model is not part of the current CDD release)
Rv2175c C-terminal domain of unknown function
This is the C-terminal domain of unknown function found in actinomycetes such as M. tuberculosis Rv2175c. Rv2175c has a DNA binding activity and possesses a winged helix-turn-helix fold, furthermore it is identified as a substrate of the PknL kinase.
Links
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Statistics
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PSSM-Id: 523230
Aligned: 36 rows
Threshold Bit Score: 83.436
Created: 19-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2KFS_A        80 VKSLPGLLTILHDGGYRDTEIMRWLFTPDPSLTitrdgsrdavsnA-RPVDALHAHQAREVVRRAQAMA 147 Mycobacterium tuberculosis...
WP_068894214  68 VKGLPGTLTVLLDAGYDDVEALRWLFTPDETLP------------G-SPVDAIRAGRHTEVKRRAQTLG 123 Planomonospora
WP_043123101  54 VDSLKGTIAVLADAGFSDEELITWLFTPDESLK------------G-RPIDALREGRKTEIRRRAQILA 109 Sinomonas humi
WP_054010584  61 VDSLRGTITVLHDAGFDDEEAITWLFTADESLP------------G-RPIDALHEGRKTEIRRRAAALG 116 Arthrobacter sp. ERGS1:01
3_pfamImport   1 VESLKGTLSVLLDSGYSDEESIVWLFTDDESLP------------G-TPMNALRTGRKTEIRRRAQALG 56 
WP_067159449  60 VTSLRGTVIVLQDAGFSDDELIDWLLTEDESLG------------H-APIESLRAGRKSEVRRIAQALA 115 Microbacterium sp. TNHR37B
WP_056005405  58 VHNLRGTLTLLSDNGFDDEAAMVWMLEDDDAI-------------GtSPIEALRAGRRSEVRRVAQALA 113 unclassified Plantibacter
7_pfamImport   1 VDGLSGTLTVLQDAGMDLVQATTWLLEGDDTFV------------G-RPIDALKQGRKKQVNSYARSLA 56 
WP_034226769  66 VPALPGTLTLLADAGFSDEAAVRWLFTPDETLRglgtg---pvrpS-TPVEALAAGHKTEIRRRAQAEA 130 Actinotalea ferrariae
WP_009155383  65 IKGLAGTITVLSDAGFTRTEMLRWLYSQDESLP------------GiTPINALRTSHGTEVKRRAQAMA 121 Saccharomonospora marina
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