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Phosphoinositide phosphatase insertion domain This domain is found in the effector protein SidP present in Legionella longbeachae. SidP functions as a Phosphoinositide-3-phosphatase specifically hydrolyzing Phosphoinositide(3)P, referred to as PI(3)P, and PI(3,5)P2. The domain is inserted into the N-terminal portion of the catalytic domain and is referred to as the appendage or insertion (I) domain. |
Jiyao W et al.(2023). "The conserved domain database in 2023.",