Conserved Protein Domain Family
Nab2p_Zf1

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pfam18260: Nab2p_Zf1 
Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1
This domain is found in nuclear polyadenylated RNA-binding 2 protein (Nab2p) present in Saccharomyces cerevisiae. Nab2p is a major family of Poly A-binding proteins whose interactions are thought to be crucial for the control of poly(A) tail length. This domain is the first of seven CCCH zinc fingers which are responsible for polyadenosine RNA binding. When combined with the next three zinc fingers (Zf1-4), these four zinc fingers together may bind RNA in the 3' to 5' direction.
Statistics
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PSSM-Id: 436370
Aligned: 4 rows
Threshold Bit Score: 53.6992
Created: 19-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_022465158 272 NFVPkRKEGRCKLFPHCPLGKACPHAH 298
XP_022629219 241 NFVN-KKQGRCQVFPRCPLGKNCPHSH 266
XP_002556150 231 NVVQ-KKQGRCKLFPRCPLGRQCPHAH 256
Q75E99       203 NIIP-KKEGRCQLFPRCPLGKFCPHAH 228 Eremothecium gossypii
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