3AFG


Conserved Protein Domain Family
Tk-SP_N-pro

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pfam18237: Tk-SP_N-pro 
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Tk-SP N-propeptide domain
This is the N-propeptide domain found in Tk-SP, a subtilisin-like serine protease from Thermococcus kodakaraensis. The beta sheet of this domain packs tightly to the two nearly parallel alpha helices 2 and 3 located at the surface of the subtilisin domain. Gln105 and Asp107 of the N-propeptide domain also bind to the N-termini of these two alpha-helices to form helix caps.
Statistics
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PSSM-Id: 436361
Aligned: 5 rows
Threshold Bit Score: 99.1342
Created: 19-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3AFG_A        14 KNYGLLTPGLFKKVQRMSWDQEVSTIIMFDNQADKEKAVEILDFLGA-KIKYNYHIIPALAVKIKVKD 80  Thermococcus kodakarensis
Q5JIZ5        37 KNYGLLTPGLFKKVQRMSWDQEVSTIIMFDNQADKEKAVEILDFLGA-KIKYNYHIIPALAVKIKVKD 103 Thermococcus kodakarensis KOD1
Q8U0C9        37 KNYGLLTPGLFRKIQKLNPNEEISTVIVFENHREKEIAVRVLELMGA-KVRYVYHIIPAIAADLKVRD 103 Pyrococcus furiosus
WP_006316919  54 KNNNKIFENLEKKLEKASDKENLPVIVVFKNKPDKN---NLKNILGNyKTKHEYKNIPAIAMELNKGQ 118 Caldisalinibacter kiritimat...
WP_068557944  54 ENKDKLFENLSKKMDKANDDEEISVIVVFKDKLDTEKKGKVKEVLGEyMAKHEYENIPAMAMKLKKGQ 121 Thermotalea metallivorans
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