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Violacein biosynthetic enzyme VioE This domain is VioE present in Chromobacterium violaceum. VioE plays a key role in the biosynthesis of violacein. Violacein has potential medical applications as an antibacterial, anti-tryptanocidal, anti-ulcerogenic and as an anti-cancer drug. VioE forms a homodimer with a chiefly hydrophobic interface between the two VioE monomers.The fact that VioE adopts a fold normally associated with lipoprotein carrier proteins may be due to VioE for binding the hydrophobic polyethylene glycol. |
Jiyao W et al.(2023). "The conserved domain database in 2023.",