3RMH


Conserved Protein Domain Family
Cdc13_OB4_dimer
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pfam18233: Cdc13_OB4_dimer 
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Cdc13 OB4 dimerization domain
This domain is found in Cdc13 proteins in several Candida species. The Cdc13-Stn1-Ten1 complex is crucial for telomere protection. This domain is the C-terminal OB4 domain and is responsible for dimerization. Dimerization of Cdc13 is important for high-affinity DNA binding.
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Statistics
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PSSM-Id: 436358
Aligned: 5 rows
Threshold Bit Score: 154.988
Created: 19-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3RMH_A        19 LNHLQHLTP-KIYVLNVYIIDVEIVYDQeIRIKVVNELPLvGKYVPPVDILEVYITGKEEVQNFLG-DEVLTMDIFTPLL 96  Nakaseomyces gl...
Q75E25       736 LQSNPLSSEgVLYLLKGKILSTVVDSSK-ATIYITNDAKL-QEEVSVRGFLRLQILGEANVSYFCG-ADEASTDVLQALN 812 Eremothecium go...
Q6FT40       623 LNHLQHLTP-KIYVLNVYIIDVEIVYDQeIRIKVVNELPMvGKYVPPVDILEVYITGKEEVQNFLG-DEALTMDIFTPLL 700 [Candida] glabrata
XP_003957764 660 LNMIRNADDmTLFNITAKLIEYDIDDEDfVNLYVTDDLIS-KKTIDPNRILKIQIFGRDNINYFKG--NNQLGIIGRELV 736
XP_003647626 777 FNSTEIYASgNLYLIKAKILSATVDGSK-VTMYLTDDAPL-RNKMNPNEVLKVEILGKSNMNYFCGdSGKTLEEELEALI 854

3RMH_A        97 NETSRLRVFQ---RPSKTDRIIRWSPIECTIQELRLQ 130 Nakaseomyces glabratus
Q75E25       813 LRAFKFYLLPgevQISPSKTARVWCPVECSIEELNSQ 849 Eremothecium gossypii
Q6FT40       701 NETSRLRVFQ---RPSKTDRIIRWSPIECTIQELRLQ 734 [Candida] glabrata
XP_003957764 737 DCQLNFKIVRsmvKLNEYTSIVSWCPIECTLEELKYQ 773
XP_003647626 855 LKTFNFFLLPakiKLSPTTSLLTWCPAECSLDDLKSQ 891
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