4TR2


Conserved Protein Domain Family
SUB1_ProdP9
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pfam18213: SUB1_ProdP9 
SUB1 protease Prodomain ProdP9
This domain is the bound prodomain fragment ProdP9 of the SUB1 protein present in Plasmodium falciparum. SUB1 is a serine protease that processes a subset of parasite proteins that play indispensable roles in egress and invasion. The C-terminal stalk of ProdP9 binds in the active site groove in a substrate-like manner and is truncated at the N terminus as a result of the chymotrypsin digestion step used during purification. ProdP9 is structural similar to MIC5 from Toxoplasma gondii, despite low sequence identity.
Links
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Statistics
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PSSM-Id: 408040
Aligned: 6 rows
Threshold Bit Score: 130.809
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
4TR2_A   139 LRLIVSENHATSPSFFEESLLQEDVVSFIQSKGKLSNLKNLKSMIIDLNSDMTDEELAEYISLLERKGALIESDKLVGAD 218
Q7RGL7   116 LRLIVSENHATTPSFFEESIIQEDFMSFIQSKGEIVNLKNIKSMIIELNSDMTDKELETYITLLKKKGAHVESDELVGAD 195 Plasmodium yoelii y...
EDL43520 123 LRLIVSENHATSPSFFEESLLQEDVVSFIQSKGKLSNLKNLKSMIIDLNSDMTDEELAEYISLLERKGALIESDKLVGAD 202
Q8I0V0   138 LRLIVSENHATTPSFFQESLLEPDVLSFLESKGNLSNLKNINSMIIELKEDTTDDELISYIKILEEKGALIESDKLVSAD 217 Plasmodium falcipar...
CAQ40517 122 LRLIVSENHATSPSFFEESLLQDEVMSFIQSKGKLSNLKNLKSIIIDLNGDMTDEELAEYINMLEKKGALIESDKLVGAD 201
CDS48132 116 LRLIVSENHATSPSFFEESLIQEDFMSFIQSKGEIVNLKNLKSMIIELNSDMTDKELEAYITLLKKKGAHVESDELVGAD 195
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