Conserved Protein Domain Family
NAMPT_N
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pfam18127: NAMPT_N 
Nicotinamide phosphoribosyltransferase, N-terminal domain
This is the N-terminal domain found in Nicotinamide phosphoribosyltransferase (NAMPT) present in Homo sapiens. NAMPT captures nicotinamide (NAM) and replenish the nicotinamide adenine dinucleotide (NAD+) pool during ADP-ribosylation and transferase reactions.
Links
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Statistics
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PSSM-Id: 497012
Aligned: 6 rows
Threshold Bit Score: 155.694
Created: 19-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
KYO38628       7 SILLATDSYKVTHYKQYPPNTSKVYSYFECRErktensklrkVKYEEIVFYGLQYILNKYLKGKVVTKEKIQEAKEVYRE 86 
VDD90753      10 NVLYLADSYKISHYKQYPVGTSHIYAYFESRG----------GKFPEVCFFGLQYFLKRWLVGPVVNKNMVEEAKDFYFS 79 
WP_058290069  16 NFLLDTDSYKYSHPQQFPKGTERVFAYIEPRRad--------gVIDELVFFGLQAELMQ-LSGQVITQAMLDEAAPFIQA 86  Tritonibacter m...
1_pfamImport   1 NLLLGTDSYKVTHWRQYPPGTTRVSSFLESRG----------GVYPSVVFFGLQYLLDRHFAGVVVTEDRIAEAREIFAA 70 
Q6WHP0         7 NIAIATDSYKVSHWSQFPRGLEYSQYYVESRGg----------KFDKIMVDGMAYMCRILEKG--VSMNDVKRAKRLFKK 74  Vibrio phage KVP40
WP_012956548   5 NICLLTDSYKLTHHYLHPKGTEKIYSYLESRTg---------AEFNKTIFYGLQYILKKYLEGNVVSEEKVLEAERIVDA 75  Methanobrevibac...

KYO38628      87 HFQ-D-DVFNEKGWNYILEKYDGHLPIEI 113
VDD90753      80 HFGgR-EIFNYDGWMHIVENHGGCLPLKI 107
WP_058290069  87 HGL---SLYT-EMFQHIIDAHDGRLPVQI 111 Tritonibacter multivorans
1_pfamImport  71 HFG-DpTLFHEAGWRHVLDAHGGRLPVEI 98 
Q6WHP0        75 HFG-S-EVFNDKGWDIIVNELKGKLPIKI 101 Vibrio phage KVP40
WP_012956548  76 HIA-P-GIFNTDDWMYIAQELDGKLPVKI 102 Methanobrevibacter ruminantium
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