2ZZM


Conserved Protein Domain Family
Trm5_N
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pfam18093: Trm5_N (This model is not part of the current CDD release)
tRNA methyltransferase 5 N-terminal domain
This is the N-terminal domain of tRNA methyltransferase 5 (Trm5) present in Methanocaldococcus jannaschii. Trm5 catalyzes the methyl transfer from S-adenosyl methionine (AdoMet) to N1 of G37. This domain, also known as the D1 domain, contacts the tertiary core (elbow) region of the tRNA L shape in a ternary complex of the enzyme with tRNA and AdoMet.
Links
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Statistics
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PSSM-Id: 523116
Aligned: 32 rows
Threshold Bit Score: 43.3181
Created: 19-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2ZZM_A         4 CLKINKKHGEQTRRILIENNLLNKDYKITSEGNYLYLPIKDVDED 48  Methanocaldococcus jannaschii
WP_015284078  13 GIRVPARQGEELRQVLIREGALDPSLKVLRDGSDLILPLRKERKG 57  Methanoregula formicica
WP_013037122   5 CVKVKKRFGEPVRQALAEMDLLDNSYRLSADDACLYVPVIDDCPE 49  Methanohalophilus mahii
Q5V2B8         5 CVRVPREAGEETRQRLAEANLVDDGYDITVVDGQLYVPVTDPTAV 49  Haloarcula marismortui
WP_011322666   5 CVRVPREDGETARGRIADADALADDYEIELDDGHLYLPIVESADE 49  Natronomonas pharaonis
WP_013898448   5 CIRVPVKMGERSRCVLLDHEILDPGYRIFSSDGYLYIPLIKEPSS 49  Methanosalsum zhilinae
WP_015324665   5 CIRVDKKKGEHVRKLLMEKGLLDTSVRIASDDSCIYIPLIPAANA 49  Methanomethylovorans hollandica
WP_013328499   7 CIKVLKKEGERTRRKLAEDGFLDNSLKPFSDEGFLYIPVTGEIPG 51  Methanolacinia petrolearia
Q2FSP5         7 CLQVHRSEGEKTRKRLLEEGVLDRLCRIRSDGEYLLIPVIRKIEG 51  Methanospirillum hungatei JF-1
WP_013193824   9 GIKVSKKKGEPTRRVLIEKGLLDASAKIFSSNGFLFLPILKQPVN 53  Methanohalobium evestigatum
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