Conserved Protein Domain Family
HTH_49

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pfam18010: HTH_49 
Cry35Ab1 HTH C-terminal domain
This is the C-terminal domain found in Bacillus thuringiensis protein Cry35Ab1 (an insecticidal protein). The domain has three helices held in a hydrophobic core, the first two form a typical helix-loop-helix whilst the third helix is perpendicular. The domain is structurally homologous to BinB and proteins containing similar beta-trefoil lectin-like domains. The domain is not required for insecticidal activity or for immuno-reactivity and its function is likely to be to bind to WCR brush border membrane vesicles.
Statistics
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PSSM-Id: 436208
Aligned: 2 rows
Threshold Bit Score: 38.1451
Created: 19-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_007203453 151 HALELLKTHTYKEVEAMTGIKKRTLIYRK 179 Fictibacillus macauensis
1_pfamImport   1 HALELLKTHTYKEVEAMTGIKKRTLIYRK 29 
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