Conserved Protein Domain Family
pre-PUA_NIP7
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pfam17833: pre-PUA_NIP7 (This model is not part of the current CDD release)
NIP7/UPF0113, pre-PUA domain
This entry represents the N-terminal, pre-PUA domain of yeast 60S ribosome subunit biogenesis protein NIP7 and homologues, some uncharacterized proteins from the UPF0113 family and similar sequences from eukaryotes and some archaeal species. NIP7 is required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly. This domain is found associated with pfam03657.
Links
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Statistics
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PSSM-Id: 522973
Aligned: 29 rows
Threshold Bit Score: 51.1115
Created: 19-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
KGO65579               1 MRSLTEEETRTLFTKLASYTGRSLNSLITpaedgSMSVFRLQGS-----RVFYVNKEIANLSVSFPRET-LLSCGTMIGK 74 
Q8TZP7                 7 ARRASSWEIDLILKEAEKF-Gtl----------vHNFFAIVEGKy---rDVYAVNNEVWKIIEDLTVRP--FALGTFVGM 70  Pyrococ...
Q58805                 3 VRKLKNAEINLIEEELSKYTDKDFVKSFK-----YENLIVLEGKw---lTVCYTNIETIKKLNMFQDIF---SVGNVFGE 71  Methano...
goetting:Ngar_c13890   4 YRRPSREERTRINRALDRW-G--TFEFFK-----DKSLMIQENDdggskAVCFVPGELEPFMRMQPPY----LAGLVIGE 71 
WP_075053566           3 FRELTRQEQTLVNRALDLW-G--VFDALK-----GKTFLVDSSS-----KVYLMSPELASVVIKVQPD----VAGLAIGS 65  Nitroso...
Q9YER5                13 LRPPTPREERLVEGFLRAI-GFKVNPYAE-----GMTVLDPGGKf---kEVFYLPWGLRRAVERLPLHY---SAGLNLGS 80  Aeropyr...
WP_013684116           7 LRGPKRREEKTIKKALSAY-D--SLDFLE-----NNVILIRDGEl---kEVFGLARELDEFLQRFPGLN-LRHAGIKLGE 74  Archaeo...
WP_012966898           3 IRRPTKKELKIIRKALAAF-G--SVDFLD-----NFSIYVKEGEk---kEVYAASKDLEAFIGKL---N-EVSFGIKVGE 67  Ferrogl...
Q6M1A1                 3 HRKLEESEISAIKAAISRYIGKK-AEELD-----FNNFLVLRGKs---kNVVHVSSQVMKSLKNHKDIY---SAGIHIGD 70  Methano...
WP_013180799           3 CRKINDEEIRTVKNLLSRYLGKN-VEKLP-----FDNILVVGNDl---kRLQYVSGDILQNILENEISYkVSSMGINLGV 73  Methano...

KGO65579              75 FTKasdisfTGKFRINL 91 
Q8TZP7                71 IKVde--nlVEKFYPAI 85  Pyrococcus furiosus
Q58805                72 I--------KRKFRLSL 80  Methanocaldococcus jannaschii DSM 2661
goetting:Ngar_c13890  72 L--------KKQFVPSM 80 
WP_075053566          66 LGK------KKQFTPTL 76  Nitrososphaera viennensis
Q9YER5                81 Ig-------ERGFRPSL 90  Aeropyrum pernix K1
WP_013684116          75 V--------GRRFRFSI 83  Archaeoglobus veneficus
WP_012966898          68 V--------GKRFRFTL 76  Ferroglobus placidus
Q6M1A1                71 LEEis---gKEKFLPSL 84  Methanococcus maripaludis
WP_013180799          74 LLIkn---dKEKFSPSL 87  Methanococcus voltae
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