5MF9


Conserved Protein Domain Family
OCRE
?
pfam17780: OCRE 
OCRE domain
The OCtamer REpeat (OCRE) has been annotated as a 42-residue sequence motif with 12 tyrosine residues in the spliceosome trans-regulatory elements RBM5 and RBM10 (RBM [RNA-binding motif]), which are known to regulate alternative splicing of Fas and Bcl-x pre-mRNA transcripts. The structure of the domain consists of an anti-parallel arrangement of six beta strands.
Links
?
Statistics
?
PSSM-Id: 496725
Aligned: 28 rows
Threshold Bit Score: 43.3773
Created: 19-Feb-2025
Updated: 28-Apr-2025
Structure
?
Program:
Drawing:
Aligned Rows:
Download Cn3D
PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
5MF9_A        11 DTSTYQYDESSGYYYDPTTGLYYDPNSQYYYNSLTQQYLYwdgEKETYVPAA 62  human
XP_046445282  35 AQSGFEYHEETGLYYDSTTQMYYNSETGLYYNGFTGTWYQydeAICEYVVHH 86 
KFB50676     102 IKNRYIFEPTSGLYYDPETGYYYNSIYGLHYDGHRGCYLKyneDTKEYDFYS 153
XP_002428513 124 KQTSFVYEPTSGMYYDYNTGYYYNAELRMYYDGNTGRYLEydeDTNTYKYHA 175
XP_014158411 274 QNTGMMWDENSGMYYNYATGYYYHTQSGLYFDPTAQAYHHlnpTTNEYEFHS 325
3_pfamImport   1 NETGLNYDKTSGTYYNSEEGYYYIPDYRLYYYPTLGAYYYydeTSDSLKFHS 52 
VDD81291     107 HNSGYVFDQQTGLYFDKNSGYYYDPDNQLFFEPKTGVYYSyndETKEYSYHS 158
XP_015794851 131 DSNDYIFEPTSKTYYSQSSGWYYYPNEKLFFDPKSKNYYTfnqETKSYDQYL 182
EDO45575     125 TKSGFVFDERTGLYYDWNSGLYYNPRTCLYYNNNTGTYYTyneSSRSYDFHS 176
Q8N302       203 SQTGFSYDENTGLYFDHSTGFYYDSENQLYYDPSTGIYYYcdvESGRYQFHS 254 human
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap