3P56


Conserved Protein Domain Family
Ydr279_N

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pfam17745: Ydr279_N (This model is not part of the current CDD release)
Ydr279p protein triple barrel domain
RNases H are enzymes that specifically hydrolyze RNA when annealed to a complementary DNA and are present in all living organisms. In yeast RNase H2 is composed of a complex of three proteins (Rnh2Ap, Ydr279p and Ylr154p), this family represents the homologues of Ydr279p. It is not known whether non yeast proteins in this family fulfil the same function. This domain corresponds to the N-terminal triple barrel domain.
Statistics
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PSSM-Id: 522918
Aligned: 111 rows
Threshold Bit Score: 37.5748
Created: 19-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3P56_B        46 LMFVKLVNPCSG-EGAIYLFN--------Mc-LQqLFEVKVF----K--------------------EKHHSWFI----- 86  human
XP_022465240  20 LKVFDLCHPSNNsSKARVKLFac-----gAedTTqIYRLEKYsfsqGgrytevsdlanekyhytgegDPVKSIIIvneqd 94 
Q6FSF0        28 AYFFELPASSNNeSSSTTKLLk------yG---TeIYQVTDYcfgkGrkyekvkdeindryhydeegKPLRSAIHvnsed 98  [Candida] glabrata
Q6CTP5        24 VEIFELPHPSNNeSKKPIKLFv------hD---DkVYQLKIKkfskGcdyncsrdlvndkyhytsdsQTFKSTFLineen 94  Kluyveromyces l...
Q75F53        58 LTVFQLPHPSNNrSKSPVRLFi------hD---GlVYQLQTQkfsrGcpynraddevneryhytadgQAYKSAIYlneed 128 Eremothecium go...
XP_003646574  26 VTVFELPHPSNNrSKKPIRVFi------hN---DvVYQLQTQkfshGcpytkeedkandryhytadnQTYKSAIVlnehn 96 
XP_002555327  17 LHIFELPHSTNInSKSKLRLFc------sD---DkIYQIKRQmfskGcaynktrdasnekyhycsdsKPLKSGILtnade 87 
XP_001644221  24 LKVFTLPSPSNNsSKGRVELFqv-----sN---NlVYQIKNHsfskGskinnnddmandvyhytrdnETLKSVILtneqd 95 
XP_056086913  25 INTFTLPPSCNIaSKPRLEIFen-----tD---GkLYEIKCFqfgkGpsyseeedlandkyhytrenNPIKSALMvntsd 96 
XP_003957443  24 LQLFTLPNPSNIkSKETLLLFqttdsvssK---DiIYRLQDHsfskPcarknseelakgtyhytnesQPIKSMFLlnedd 100
3P56_B        87 --NQSVQSGGLLHFATPVD 103 human
XP_022465240  95 rsDGYVIEDSTFDISNKYD 113
Q6FSF0        99 ktNYTVLPNANIKYFSKYD 117 [Candida] glabrata
Q6CTP5        95 rkDGHILEDGSILYAEKYD 113 Kluyveromyces lactis
Q75F53       129 psQSLVLESGEFDYHTKYD 147 Eremothecium gossypii
XP_003646574  97 peESFVLESGTFEYHTKYD 115
XP_002555327  88 rrDGWLLEDGYFEFTTKYD 106
XP_001644221  96 rsEAYLRENGSFKFALKYD 114
XP_056086913  97 saDGYIFKSSKIYFCTLYD 115
XP_003957443 101 rkDGYVLESSTFKHATIYD 119
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