Conserved Protein Domain Family
FIMP
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pfam17672: FIMP (This model is not part of the current CDD release)
Fertilisation-influencing membrane protein
In mice, 4930451I11Rik encodes two isoforms: a transmembrane (TM) form and a secreted form. FIMP is the TM form. It is a sperm-specific transmembrane protein that is essential for the sperm-oocyte fusion process.
Links
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Statistics
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PSSM-Id: 522877
Aligned: 3 rows
Threshold Bit Score: 142.726
Created: 19-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_005591661  26 VPRPKRATASVLGTESPRFLDRPDFFDYPDSDQARLLAVAQFIGEKPIMFVNSGSSPGLFHHILVGFLvVVV-FFLLFQF 104 crab-eating mac...
XP_003795833  22 APSPKSTKALAPGMESPVFIDRPDFFDYPDSDQARLLAVAQFIGERPVIFTRSGSDLGLFHRILVGAL-VVAfFFLLFQF 100 small-eared galago
XP_003434858  37 APRRENANVLARGAESLLFIERPDFFDYPDSDQARILAVAQFIGEKPVIFVNSGSNSEFFHHILVGAL-VVAfLFLLYQF 115 dog

XP_005591661 105 CTHINFQKGA 114 crab-eating macaque
XP_003795833 101 CTHVSFQKGA 110 small-eared galago
XP_003434858 116 FIHMTCQKGA 125 dog
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