Conserved Protein Domain Family
ASPRs

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pfam17641: ASPRs 
Ancylostoma-associated secreted protein related
This family includes members encoded by ASP-related genes which are distant homologs to ASPs (Ancylostoma-associated secreted proteins). ASPs are a diverse set of secreted cysteine-rich proteins pfam00188. ASPRs, on the other hand are predicted to be secreted with one ASPR in Heligmosomoides bakeri shown to be secreted by parasitic adults. Thus, like ASPs, ASPRs are suggested to comprise an important element of hookworm infection in vivo.
Statistics
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PSSM-Id: 407540
Aligned: 41 rows
Threshold Bit Score: 87.0747
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EYC21938      83 CE----------ASKMLL-GPCRKVIKLPLLEEISEKmsd-kqLQYDCELEDAALgKLLLDADVAdfylKLFPQANGTTq 150
EYC44560      21 CTg--------lGKYTMQ-SDVKDHVVQRVLLYSPGKeiasisSVYDCDLEKMAG-EILDDPHKP----IAFLKDIGIYp 86 
EYC44552      33 CPg--------lGDHTME-QDVKDDLIPKVLRYSLDQevasisSVYECNLEKIAG-EILADPYKR----IQFLPDIGIYp 98 
EYC44553      17 CPg--------lGEHTMQ-QDVKDDLIPKVLRYSPDQdvaslsSVYDCNLEKMAA-EVLADPYKP----IKFFENIGIYp 82 
EYC44561      21 CTe--------lGEYAMQ-RDVKDDLIPKILRYSPGQdiasvsSVYDCDLEKMAS-DLLTKTYKT----LDFLKPIGIYp 86 
EYB91808      26 CSq--------lGKYALD-PDLRERLATEIIANQPIKdvs-vpLVYLCALEGMAG-LILENSQKP----LNCLSDLGIFp 90 
EYC44562      33 CSq--------lGKYAFHrKDLRTELAAELLVRQPTRggvsakMTYLCALEGMAG-LILENPHKP----VTCPVDLGIFp 99 
EYC23862      26 CSq--------lGKYAMPsSDQRMVLFTGVEALAPSKdvg-lkIVYECALEGMGG-LILESPEKP----YNCAQSLGIFp 91 
EYC23863     104 CTq--------lGVYAMP-YDQGMELLLGVEARAPKGemg-skLVYECALEGMAG-LILKSRRKA----LCCPKTLGIFp 168
XP_013291320  24 CSklegfamagvDKFTLNdSSIRDQLYSGILQYATQSp----dIKYDCSVELAGG-LVLDDPAKD----FRFLMSNGRFp 94 
EYC21938     151 LQFnetrteTTLTHTEANDFVSKAVQSWSSRLEEMKTNTsn-----aaKYGCNFAveKGFRYTLLCLF 213
EYC44560      87 LIYs----iEGRGEDNVRLMTHAALHTWKEYIEKIPFF----------TFGCNYRkqYGDRHYYLCLL 140
EYC44552      99 LLYy----iEERGEDNVRLMTHAALQNWLKNLKNLHYF----------NFGCNYRfeHG-MHNYLCLF 151
EYC44553      83 LVYn----iEERGEDNVRLMTHAALQYWKKYLENLHYF----------NFGCNYIyeHE-MHKYLCLF 135
EYC44561      87 LIYs----iDGRDENNVRLMTHAALQTWKNYIEDIPFL----------TFGCNYRyeNG-MHNYLCLL 139
EYB91808      91 LITe----mDDEADAGVDALAKAAVGEWALHIPRLTFAS---------SFGCNHVleDG-RHIYLCLF 144
EYC44562     100 LLFe-----KDGKDVSANLMTKEATADFVKHMPAFGSAT---------GFGCNYVeeNG-RHKFLCLF 152
EYC23862      92 LIF------EIDEGTDVNAANNAAIKHWENHIPNLRGRS---------GFGCNYIkeQG-KHRYICLF 143
EYC23863     169 LIFe----mMDGPGTNATETNQAVLEAWDKHLPNLGKIS---------SFGCNYIhqEG-KHRFLCLF 222
XP_013291320  95 LISe----tDGNST--VEVATQAALKLWEKHIPNVRKAScdvklgpreAVGCNYVf-eDDRHKYICIF 155
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