Conserved Protein Domain Family
RPS12
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pfam17487: RPS12 
Ribosomal protein S12
This is a family of unknown function. Family members are ribosomal proteins found in the mitochondria (RPS12). Homologus RPS12 proteins in bacterial ribosoms participate in stabilizing the second base pair of the codon-anticodon duplex in the A site and is likely to be critical for the fidelity of decoding process. A similar role can be anticipated for this protein in mitochondrial ribosomes. This has been shown where the product of edited RPS12 mRNA translation represented a component of the mitoribosome's small subunit.
Links
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Statistics
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PSSM-Id: 407518
Aligned: 5 rows
Threshold Bit Score: 73.1666
Created: 22-Aug-2024
Updated: 4-Dec-2024
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q31761    4 IFFIRGFYLYGLCLRLFIFLCVYYISPRLPSSGNRRLCCSIFWLSNIIFYVSVFFCCIYFVVFSqQLFIVEGGGFIDLPG 83  Crithidia fasciculata
O47756    1 MFFVRSYCLYGFCVRFCFVFLCIYVSPRLPSSGNRRVYVVCFNLYSFVIYCFLFGCCVICYSQS-FYFLCEGGGFVDLPC 79  Phytomonas serpens
AFD61592 13 LFFCRSLYLYGLCCRFCLFISIFYVSPRLPSSGNRRIVLAVFYLYNFVWVIRVFFCCVFSVGLF-SLFIIEGGGFIDCPG 91 
Q33569    2 LFYC--VLLYGLCLRFLLFSFRYFMCPRLPSSGNRMIGCLLLLLFYSFWLLRCFF--IFFLVSC-FIYVVEGGGFIDLPS 76  Trypanoplasma borreli
ADK12975  1 MYFVRVLYLYGLCVRFLFLCLVLYLSPRLPSSGNRRCLYAISIMFNILWYFLVF-CCFVFVIFQ--LFIVEGGGFIDLPG 77 

Q31761   84 IKYYSRFF 91  Crithidia fasciculata
O47756   80 IKLYVRVP 87  Phytomonas serpens
AFD61592 92 LKLFTRFI 99 
Q33569   77 LRYFTRLF 84  Trypanoplasma borreli
ADK12975 78 VKYFSRFC 85
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