Conserved Protein Domain Family
DUF5332
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pfam17266: DUF5332 (This model is not part of the current CDD release)
Family of unknown function (DUF5332)
This family of uncharacterized proteins is mostly found in Chromadorea. Family members include dct-5 proteins. Dct-5 is a target of DAF-16, a forkhead transcription factor, which is a key regulator of longevity, metabolism and dauer diapause in Caenorhabditis elegans.
Links
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Statistics
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PSSM-Id: 522787
Aligned: 10 rows
Threshold Bit Score: 161.808
Created: 19-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
VDN54760      40 RYLVEKFNGAVINKRLYSDLDSSIDYGCIFTSGCSDECNNCPLCLTSKEQLVDVLSGTRRAlnGECSTLVNCATDCVAQS 119
VDN03470      54 PFIADRFNGPLITAQHYNDLDTGIDYGCIFTAGCLDECNKCPLCEMSKQQLIDVLNGVKRTpqGECSVLVNCAADCLKRS 133
VDN90548      45 SYIINRFNDSIINKEMYNDLDKSIDYGCIFTVGCLDECNNCPICKLSKEQLIDVLSGSERSseNECSVLVNCATKCIQQT 124
3_pfamImport   1 PYITGQIDGSLINKKIYNDFDEGIDYSCIFATGCFDECNNCPLCQTSKQQLIDVLSGNERSstSECSVLVNCASKCVQQS 80 
O16887        43 PVLSKLVDGKNISAEMYDDIDKYTDYGCIFTTGCQDECNDCPLCLTSKLQIVDILSGEKSS--AECPTLMDCALKCVAES 120 Caenorhabditis ...
2_pfamImport   1 DKCIPTLTKLPPQEKLISLLLDKTNFACILGPTCYEYCSTCDSCKYAQEQMKRIILGTELE--GQCKNLEECAETCISDG 78 
1_pfamImport   1 SACFRRDINRLVTMAILPHFASRFDMVCI-AAKCSNECQACKECHYAIEQMSALAQGEPTS--GLCPKLESCVQSCLQVV 77 
KHN73164      41 SEKVHRAIYNSTADDMFSTILNQFSFLCI-ASKCRSDCRNCEQCQYALSQIKNLASGSHTE--MQCPKMEQCSEQCMRA- 116
5_pfamImport   1 TAKTNESTNSSSGIEIFNNMINQFNFICI-ATKCRDPCTACEQCNYALEQFSKILRGLKTD--MKCPKMETCLLKCLHEN 77 
A8WUE9        33 KDMVRKIVIESSREEVFGNLVEKFDMVCI-AAKCGNECSQCKHCHYALEQMSALAQGEKTS--GLCPKLETCVFNCLTE- 108 Caenorhabditis ...

VDN54760     120 NANFT---TINYCL-RHLCAFHCFDG-SCNKCSAFVTRLFNQICVSAGFRRMVk-QFDGQCYELFKQIVYSKFKEQFK 191
VDN03470     134 NSNFT---VINYCF-RHECAYHCFDG-TCPICSTFITRLFNQACVSGNLRRKM--NFQGQCYEMFRAMVYAKFKQQFR 204
VDN90548     125 NFNFI---KTNYCL-RHQCAYHCFDG-SCPTCSAFVTRIFNQICIKGNLRKRI--NFKGQCYEMFREIVYKKFEKKFK 195
3_pfamImport  81 NFDFT---RINYCL-RHQCAYHCFDG-SCPKCSAFITRLFNQICINGDLRKKT--NFMGQCYEMFRAIVSEKFEEQFK 151
O16887       121 NQDIF---QINKCL-RQDCAFHCFDG-SCPKCSGFITRVFNQMCAAGNFRQKIk-GYSGPCYEMFHEIVRAKFADRFE 192 Caenorhabditis el...
2_pfamImport  79 LKD------PFKCVfYSRCANFCLDNiDCPKCYDMVKRVFIGYCVRSNFMD----HYKTKCRELFSQLSIDFVRNFNK 146
1_pfamImport  78 SQSFSsrfPIIACV-ARRCNVHCYDG-DCSSCRTISKRMFTIICQQTDMPKLPhiQYTGTCPHLFNELADDYVAGRKR 153
KHN73164     117 DLQ-----RAIPCV-KKRCNVHCFDG-DCPQCASVAKRVFLFMCREHNVPNLPlvSYNGSCMALFDVVVQNYIALRTN 187
5_pfamImport  78 GF------QFGACA-RERCNPHCFDD-ECSYCTYLARRIFLKICRENNIPTLSnvNFNGKCIDLVNNVLKEVASSRKT 147
A8WUE9       109 DVS-----KVLSCV-ATRCNVHCYDG-DCPSCKMISRRIFSTICKQHSMTSQPqiKYEGTCPNLFMELADHYVAKKKl 179 Caenorhabditis br...
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