6VDA


Conserved Protein Domain Family
ZT_dimer

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pfam16916: ZT_dimer (This model is not part of the current CDD release)
dimerization domain of Zinc Transporter
ZT_dimer is the dimerization region of the whole molecule of zinc transporters since the full-length members form a homodimer during activity. The domain lies within the cytoplasm and exhibits an overall structural similarity with the copper metallochaperone Hah1, exhibiting an open alpha-beta domain with two alpha helices (H1 and H2) aligned on one side and a three-stranded mixed beta-sheet (S1 to S3) on the other side. The N-terminal part of the members is the Cation_efflux family, pfam01545.
Statistics
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PSSM-Id: 522641
Aligned: 311 rows
Threshold Bit Score: 52.0801
Created: 17-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6VDA_A        10 DMYDDIFAVLERFPNVHNPHRVRIRRVGTKYFIEMDIEVDGKMSVKDAHELTVKIRKEMLkRRDDIEDVTIHVEP 84  Thermotoga maritima ...
WP_012958727 220 EKTKPFMETILSVKGVKRVDELLARNHGHYVVIDLKVSVEPHISVEDGHSISKKVKSNLLnTHQNVKKVMIHINP 294 Alkalihalophilus pse...
WP_013488670 219 ESTKPFFNTALAIEGVKRVDELFARTHGHYIVVDIKVSVDPHISVEEGHFISKEVKKLLLdNHQDIKKVLVHINP 293 Evansella cellulosil...
Q9KDH5       221 EDTVEMREAAKSVDGVMNLDAFHAREHGHYVIIDIKIAVNPRMTVEDGHTIAKAVKERLMlE-PNVHDVFVHVNP 294 Bacillus halodurans
WP_014371937 214 EDAADLIETVQRVKGVIAVDDLQARELGHYVIVDVRISVNPRITIQEGHEIARIVKQTLMkRFSHITEVLTQVSP 288 Paenibacillus mucila...
WP_012811375 220 EALQPYRREVLRVPGVRAIDEIRVRDHGQYVIVDIEIAVDADITVLAGHDIAAAVRDRLReKFDRVQDVFVHVNP 294 Alicyclobacillus aci...
WP_013373488 220 EEIESYAAAALSVAEVQRIDRIRAREHGHYIIVDIRASVDASLTIQQGHDIIRLIKRAVMkREPRVYEVLVHLNP 294 Paenibacillus polymyxa
C0SP78       219 ELIEEYKAVIFQCDQVKRIDRIRAREHGHYKLLDVRLSLDHDLTIKQGHDIAREIRNEIKrQFSDVEEVLIHVNP 293 Bacillus subtilis su...
Q2LXF8       214 ELICEIAAEVDKIPAVERVHEVRCRRSGQYLIMTLKLEMDPNMTVKDSHEATVLVKKRLFeKFTNVGDVTIHVNP 288 Syntrophus aciditrop...
WP_012530860 214 ELLRAITLLAERVEGVDQVHEIRARHSGQFLIVDLKLDMDPEMTVKRSHAIATQVKEEIFdQFNNVGDVMIHINP 288 Citrifermentans bemi...
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