2QLY,5KZW,3TON


Conserved Protein Domain Family
NtCtMGAM_N
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pfam16863: NtCtMGAM_N (this model, PSSM-Id:465286 is obsolete)
N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase
NtCtMGAM_N is a beta-barrel-like structure just N-terminal to the catalytic domain of maltase-glucoamylase in eukaryotes. It contributes to the architecture of the substrate-binding site, by donating a loop that comes into close contact with two regions in the catalytic domain thereby creating the site. This family is frequently found at the N-terminus of Glycosyl hydrolase 31, pfam01055.to which it contributes as above.
Links
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Statistics
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PSSM-Id: 465286
Aligned: 311 rows
Threshold Bit Score: 62.4988
Created: 26-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2QLY_A         64 G-FTARLKNLPSS--P-VF--GSN-VDNVLLTAEYQTSNRFHFKL-T----DQTNNRFE-VPH--EHVQ-----SF---- 119 
Q21750         68 QgSTYNLRKNGGP--SnPW--GAD-STEIKLTTKSIG-SVLNVKI------GIDG-RYE-PP---VDFPr---------e 121  Caenorhabditi...
13_pfamImport   1 SgSTYNLRKNNGP--GnPW--GGD-FTEIKLTTKTIG-NVLNVKV------GVDG-RYE-PP---VDFPrss-------- 55  
CAP30446       72 IgSTYNLRKNNGP--RnPW--GAE-FENIQLRTSTIGASVLNVKI------GIDG-RYE-PP---VDFPr----ET---- 127 
EWS71987       80 NyVEMIIKLNKQI--DiVYteNKI-YQQLKVVVDCNSWDELSFRI-T----DIDEKRFE-LPHr-EPFPyt--kNK---- 143 
Q22RK7         62 S-FTAILSWVKGKkeKeLN--SSPvVKDLRVTFKVDANDECQFKI-T----DLSNSRFH-LPEn-EPYPft--kQRf--- 126  Tetrahymena t...
Q22RJ9         62 S-FSAILKWIPSPneIeLK--TSPvIRDLRATFQVDANDECEFKI-T----DLNNSRFH-LPEn-EPYPyt--kQRy--- 126  Tetrahymena t...
XP_001013182   34 GtVVQQKFKRNSQslPnGI--QNV-VEDIQILITSQDANILDIQI-Kp--lEKTDKIYEfIE----LEPfnslyNEtinn 103 
EFX80346      175 S--------------SdMF--GNV-MPTARIVVRAVNRDHLVVQMiApgqlEDDSFRLV-TADerTPFS----------- 225 
EPS36110       58 K-FIAQL--RGKTghTtRY--GPS-VDRLQVEIDAFTPTIARISI-T----DLDKQRWE-IPQ--EMVPlgqdlRP---- 119 

2QLY_A        120 SGNAAASLTYQVEISR--QP---FSIKVTRRSNNRVLFDSSIGP--LLFADQFLQLSTRLPS 174 
Q21750        122 TQSSTESLSLSTSFSN--GV---FSFSVVRQSTNRKLFDTSIGG--LIFSDQFIQIATYLPS 176  Caenorhabditis elegans
13_pfamImport  56 -ipSSDSLTLETSSGN--DF---FSFGVVRQSSNRKLFDTSIGG--LIFSDKFIQIATYLPS 109 
CAP30446      128 -ISTPETLSFTTASSD--DL---FWFSVIRNSSNRKIFDTSLGG--LIFSDQFLQLSTYLPS 181 
EWS71987      144 -SWSLKKQRYEFQLPSvgEK---FYFRLVRKVTKEIIFDTSDFD--LVFTDKYLEISTALNQ 199 
Q22RK7        127 SKKQQEFNLFETEISQvgQK---FYFELRRKSTKEIIFSTKNFP--IYFTDKYIEVTTQMKD 183  Tetrahymena thermophila SB210
Q22RJ9        127 SKKQKEFNLFETEISQvgQK---FYFELRRKSTQEVIFSTKDYP--IYFTDKYIEVSTQMKD 183  Tetrahymena thermophila SB210
XP_001013182  104 NVKSESEYIYSTEIIN-------NGIKVTRKETNEVIFDT--SPfsFLLNQVYMEVSTIMPT 156 
EFX80346      226 ------QTDFQVSVTT--EKktsFAIVVRRASTGEVLLDTSYGP--LAISDEYVEMSTTVPS 277 
EPS36110      120 ENMYTGEANYDLAFDEkgKD---VGFAIFRKSDGEAVFDSRGLP--ISFCEHYMEISTKLPE 176
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