4DHX


Conserved Protein Domain Family
CID_GANP
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pfam16766: CID_GANP (This model is not part of the current CDD release)
Binding region of GANP to ENY2
CID is a domain on higher eukaryotic germinal-cent associated nuclear protein, or GANP, that binds to the transcription and mRNA export factor ENY2. The complex of these two proteins forms part of the TREX-2 complex that links transcription with nuclear messenger RNA export.
Links
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Statistics
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PSSM-Id: 522557
Aligned: 12 rows
Threshold Bit Score: 82.8685
Created: 17-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
4DHX_A          4 VLSELSQGLAVELMERVMMEFVRETCSQELKNAVETDQRVRVARCCEDVCAHLVDLFLVEEIFQTAKETLQ 74   human
XP_003463200 1158 VLTQLSQGLAEELTELMVTECVWETCSQELKNALEIDQRVRVTRCCEAVFTQLVDLFLAGEIFQTAKETLQ 1228
4_pfamImport    1 VLSQLSQGLAAELAELVVMECVRETCSREWMSAVETDQRARVARCSEDVCAQLVDLFLREEVFQTAKGTLQ 71  
2_pfamImport    1 LLAPLSQVPATQLMD------VQETSSRELKSVVETERRTRVARCSEDVCDHLMDLFLAEEIFQSAQETLQ 65  
XP_056676144 1220 LLAQLSQALAVELMDLVVAECVRETSSRELKRAVETERRACVARCSEDVWDHLMDLFLEEEIFQSARETLQ 1290
XP_008112685 1138 LIKTLSESMSANLTDEIINEMIQEISTMELRCAREKDQKARIARCSKEVCAEIMGTFLEDEIFQSAKETLQ 1208
XP_023192446 1419 FLAQFSCSLCSEVVQQVVAEVVRETAAAEIQVAVA-EQAERLARCSDQICSSLIEETLAADVAQLAEDVLE 1488
XP_006636742 1352 LIAQISKALCEEIAKEVLKECIEATAACEIKQALE-EKAACVARCSEDACNTLIEETLESEISKLANDILT 1421
KAG9271617   1287 FLDKLSSELCVEICEEVLAQCSEEVAGAEIKFALE-EKAAFLARCSEEVCSSLVVETLDAEITQLAKEVLN 1356
XP_014988163 1164 VLSELSQGLAVELMEHVMMEFVRETCSQELKNALETDQRVRVARCCEDVCAHLVDLFLVEEIFQAAKETLQ 1234
XP_064419564 1413 FITRYSQALCKQLAEEVLAESVKDIANTELQCAVEEDRTIRITICSEEVSDSLLDQTLEEEIFQTGKETLQ 1483 coelacanth
XP_028924451  273 VITQLSQALVEDLTEVIVKECVRETSSRELKCAVEIDQRARVARCSEDVCVRLMDLFLEDEIFQSAKETLQ 343  platypus
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