5IKJ


Conserved Protein Domain Family
Clr2_transil

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pfam16761: Clr2_transil (This model is not part of the current CDD release)
Transcription-silencing protein, cryptic loci regulator Clr2
Clr2_transil is a domain carrying the first and second of three regions on Clr2 that are necessary for transcriptional silencing by the protein. Clr2 is a protein in the SHREC complex that is a crucial factor required for heterochromatin formation and it plays a major role in mating-type and rDNA silencing. The third region is family pfam10383.
Statistics
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PSSM-Id: 522554
Aligned: 68 rows
Threshold Bit Score: 58.8021
Created: 17-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5IKJ_A       142 YYLASLPTNYQLYQRDSNRENGNg----KREFWL----YGHPSG------RPFRSVNDFLHHLYWLISDLTRN---ESTC 204 Schizosaccharom...
XP_009270501  73 YQLQSLPEGYRLYAFDSKENGIN-----QKVTFL----FGSIHV------KKFTSIKAFTPHAVWLKTDRKQR---HENC 134
XP_007404359  74 YSLKNFPKNYYLYKYANYGPSTM------DKTVL----YGDCPPkrfwsyRHFASSHEFLLHLYWLCTNSREA---VGKC 140
XP_007402394  98 gRLVSFPEGYELISVPRLGDAQR------HDLYLirphYDD---------DEYRSPAEFGPHLAWLMAGQPRDaggRPVC 162
XP_007400794 147 gRLHSFPAGYTLMYIPRLKDSDH------KDVYL----YSTDGK------RKWRSPEEFGPHLAWLLTGQRRDi--AGRC 208
EPS43998      77 WVLEALPANYQLYAHKKPNTEELsakklASTGHF----FGLKVGnn---nVVFQSPEEFLPHLTWLGSDRSQS------C 143
XP_002173970  89 YVLGELPQNYELFVKVGARNNTSa----KADLWL----FGHPSG------RPFRSAVEFQPHLYWLVTDLTHD---VQKC 151
O13881       131 YYLASLPTNYQLYQRDSNRENGNg----KREFWL----YGHPSG------RPFRSVNDFLHHLYWLISDLTRN---ESTC 193 Schizosaccharom...
XP_013022456 144 YVLEALPKHYQLYQRDLNRDSSGa----KREYWV----YGHPGG------RPFRSMNDFQHHLYWLISDLSRN---GANC 206
XP_011117696  77 WVLEALPANYQLYTHRKPNPEKLtakqlASTGLF----FGLRAGns---nLAFQSPQDFLPHLIWLESDKSKA------C 143 Orbilia oligosp...
5IKJ_A       205 CCV 207 Schizosaccharomyces pombe 972h-
XP_009270501 135 KCN 137
XP_007404359 141 QCR 143
XP_007402394 163 DCC 165
XP_007400794 209 VCE 211
EPS43998     144 TCH 146
XP_002173970 152 CCV 154
O13881       194 CCV 196 Schizosaccharomyces pombe 972h-
XP_013022456 207 CCS 209
XP_011117696 144 TCR 146 Orbilia oligospora ATCC 24927
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