Conserved Protein Domain Family
STAC2_u1
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pfam16664: STAC2_u1 (This model is not part of the current CDD release)
Unstructured on SH3 and cysteine-rich domain-containing protein 2
STAC2_u1 is a region of natively unstructured but highly conserved sequence between C1_1 pfam00130, and an SH3 domain, eg pfam00018, on SH3 and cysteine-rich domain-containing proteins from higher eukaryotes. The function is not known.
Links
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Statistics
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PSSM-Id: 522474
Aligned: 15 rows
Threshold Bit Score: 139.889
Created: 17-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_015212663 166 KGFRRYYSSPLLIQEQFGCI-----------------KEVMP---IACGSKVDPVYETLRFGTSLAQKTkRSStgsGSES 225
7_pfamImport   1 KGFRRYYSSPLLIQEQYGCI-----------------KEVMP---IACGNKVDPVYEALRFGTSLAQRTkRAS---GSES 57 
XP_035159209 167 TSFRRNFSSPLLVHEPPPACat--------------sKESPPt--AGASGKVDPVYETLRYGTSLALMN-RSSfssTSES 229
XP_002940986 167 SSFRRNFSSPLLIHETQSSP-----------------KEIPPp-aTGPKGKVDPVYETLRYGTSLAHLN-RSScssVSES 227
XP_008111529 164 ASFRRNLSSPMLLHDPQPQPatttttstatvtaaattKESLPa--AGTSGKVDPIYETLRYGTSLAYMN-RSSfssTSES 240
XP_006638324 183 GAFKRNFSSPLLVNDQLGVV-----------------KEAPP---SAVKNRIDPVYETLRYGTSLAQMS-RSSfgsVSES 241
1_pfamImport   1 GAFKRNFSSPMLVNDQLSVV-----------------KEVQPsqaEAVRMRVDPVYAALRYGTSLAQMS-RSSfgsLSES 62 
6_pfamImport   1 GAFKRNFSSPMLVTDQLAVV-----------------KEVQPs-qEAPRMRVDPVYAALRYGTSLAQMS-RSSfgsLSES 61 
XP_023813187 275 GAFKRNFSSPMLVNDQLSVV-----------------KEVLPs-qETARMRVDPVYAALRYGTSLAQMS-RSSfgsLSES 335
XP_029692821 180 GAFKRNFSSPMLINDQLSVV-----------------KEVQPs-qETARIRVDPVYAALRYGTSLAQMS-RSSfgsLSES 240 torafugu

XP_015212663 226 PHRNSttdlaevpeesdGHSLP------GHTGHTR--------KLSDSVFTslenGTEHFHSEEKKPET-----SP---- 282
7_pfamImport  58 PHRNSts---------dLDKVP------EEVVAHSsrqe-lsrKHSDDVFT----VIENGTEQYHHPERkpdslQM---- 113
XP_035159209 230 PTRSL------------SERDE------LTEDGEGsvrs-seeGPGDSASPv---FTAPAESEGPGPEEkspgqQP---- 283
XP_002940986 228 PTRSL------------SEREE------RLEDPEGsirs-seeSPSHPVF--------PAETEAAVSEDarsvsSL---- 276
XP_008111529 241 PTRSL------------NEKDEegpkdeGTEDTEAggqt-teeTQADNVFS------GPAESEGTISEEkspeqQS---- 297
XP_006638324 242 PTRSM------------SERSE------GAEDGEDsqrsteeeGIQG-----------PGESEKAGSEDr----VS---- 284
1_pfamImport  63 PTRSL---------------NE------QGDVKHKgeggvrqsLAPPPSDVs----vPDVEVEKEEDEScsgapTP---- 113
6_pfamImport  62 PTRSL------------GEGGE------EMQQRQSsme---eeLTQETGDA----PIPEPEIEKEVEESseqtqTA---- 112
XP_023813187 336 PTRSL---------------GE------GGEERQQrqcsmeeeITLETGDT----LVADEEMEKEVDESseqaqVLseds 390
XP_029692821 241 PTRSV------------GEGGE------ESEQRRQfsv--eeeHSQEAAAPd--aAVCSTDAEKEEEEPgtqaqTAaees 298 torafugu

XP_015212663 283 -VK-IQQRKDILQLN 295
7_pfamImport 114 -EQ-SMLQKDVLKLN 126
XP_035159209 284 -PK-APLRKDVGPMY 296
XP_002940986 277 -AAaGRARKEISPMY 290
XP_008111529 298 -AR-ASARKEISPMY 310
XP_006638324 285 -LK-APARIEVSHMH 297
1_pfamImport 114 -AE-VPKRIEVHSIH 126
6_pfamImport 113 -EEkVPKRIEVHSIH 126
XP_023813187 391 sAK-IPKRIEVHSIH 404
XP_029692821 299 sVK-VPKRIEVHSIH 312 torafugu
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