3WYB,2DAP


Conserved Protein Domain Family
DAPDH_C
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pfam16654: DAPDH_C (This model is not part of the current CDD release)
Diaminopimelic acid dehydrogenase C-terminal domain
This family comprises the C-terminal domain of diaminopimelic acid dehydrogenase. Diaminopimelate dehydrogenase is a NADPH-dependent enzyme that catalyzes the oxidative deamination of meso-2,6-diaminopimelate, which is the direct precursor of L-lysine in bacterial lysine biosynthesis.
Links
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Statistics
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PSSM-Id: 522467
Aligned: 46 rows
Threshold Bit Score: 255.231
Created: 17-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3WYB_A       122 GWDPGLFSLNRLLGEVVLPVGNTYTFWGKGVSQGHSDAIRRIQGVKNAVQYTIPIDEAVNRVRSGE-NPELSTREKHARE 200 Ureibacillus th...
WP_013669261 118 GWDPGLFSLNRLLAETILPQGQTYTFWGRGVSQGHSDAVRRVDGVKAAIQYTVPNQAMLEAAKAGD-PIDYQQATAHSRE 196 Aerococcus sp. ...
WP_010080205  58 GWDPGLFSVNRVLGAALFPQPQQNTFWGKGLSQGHSDAVRRVPGVRRGVQYTIPSEEAIAEARAGR-GAEITGASAHVRE 136 Micrococcus luteus
3_pfamImport   1 GWDPGMFSLNRVYAAAVLPGAQQNTFWGPGLSQGHSDALRRIEGVASAVQYTLPAEEALDKARRGE-AEGITGKNAHKRQ 79 
P04964       118 GWDPGMFSINRVYAAAVLAEHQQHTFWGPGLSQGHSDALRRIPGVQKAVQYTLPSEDALEKARRGE-AGDLTGKQTHKRQ 196 Corynebacterium...
WP_015401815 121 GWDPGMFSLNRTLAKAILPTAQQHTFWGPGLSQGHSDALRRIEGVRKAVQYTIPSEDALGSARRGE-AGDLDGKQAHVRR 199 Corynebacterium...
WP_020935612 118 GWDPGMFSLNRTIADALLPGNEQHTFWGPGLSQGHSNAVRRIDGVQKAVQYTLPDEDSLELARQRK-AGDLDGKSAHVRK 196 Corynebacterium...
CDA92599     127 GWDPGLFSLSRMLAEALLPCGESYTFWGRGISQGHSDAVRSIEGILDARQYTIPKEDVLKKIRTGEiCNALSDRQCHRRE 206
WP_014586008 123 GWDPGLFSLIRLLEEAVLPEGTDYTFWGPGVSQGHSDAVRRVEGVRDARQYTIPIEDTVARVRSGE-APSLSTRERHLRR 201 Methanothrix ha...
2DAP_A       118 GWDPGMFSINRVYAAAVLAEHQQHTFWGPGLSQGHSDALRRIPGVQKAVQYTLPSEDALEKARRGE-AGDLTGKQTHKRQ 196 Corynebacterium...

3WYB_A       201 CFVVLE--EGADPAKVEHEIKTMPNYFDEYD-TTVHFISEEELKQNHSGMPH--GGFVIRSGKSDEGHK-QIIEFSLNLE 274 Ureibacillus th...
WP_013669261 197 VYAVLE--EGADPDQVAKAIKTMPDYFAPYDqVDVHFISQEELDQNHQGIPH--GGEVVRQGQTSADHH-AVYNFALQLG 271 Aerococcus sp. ...
WP_010080205 137 CYVVA---DEADHA----AITTMPDYFAPYE-TTVHFISEEEFERDHQGMPYvrECHVVTSGDLGGSR--SAVEFVLELE 206 Micrococcus luteus
3_pfamImport  80 CFVVPEsdDAALKERIENDIRTMPDYFVGYE-VEVNFISQEEFDKNHTGMPH--GGHVITTGELGATRThHTVEYTLELD 156
P04964       197 CFVVA---DAADHERIENDIRTMPDYFVGYE-VEVNFIDEATFDSEHTGMPH--GGHVITTGDTGGFN--HTVEYILKLD 268 Corynebacterium...
WP_015401815 200 CFVVC---DAADEERIENEIRTMPDYFVGYQ-VEVNFIDEATFDAEHTGMPH--GGHVVTAGDTGGFT--QSIEYTLELE 271 Corynebacterium...
WP_020935612 197 CFIVA---DEADHERIEHEIRTMEDYFVGYQ-VEVTFVDEATFDAEHTGMPH--GGHVITAADTGGFN--HTIEYILKLE 268 Corynebacterium...
CDA92599     207 CFVVCE--DGGNPKKIRRKILHMPDYFEGYE-TEVHFISQEELQEKHSKMPH--GGTVIRVGKTGGENK-AVYDFSLKMD 280
WP_014586008 202 CYVVAE--EGADPGEIREKIRSMPNYFADYD-TKVSFISQEEMERSHNRMPH--GGFVMRAGKTADGTG-HVLEFRLKLD 275 Methanothrix ha...
2DAP_A       197 CFVVA---DAADHERIENDIRTMPDYFVGYE-VEVNFIDEATFDSEHTGMPH--GGHVITTGDTGGFN--HTVEYILKLD 268 Corynebacterium...

3WYB_A       275 S 275 Ureibacillus thermosphaericus
WP_013669261 272 s 272 Aerococcus sp. Group 1
WP_010080205 207 S 207 Micrococcus luteus
3_pfamImport     -    
P04964       269 r 269 Corynebacterium glutamicum ATCC 13032
WP_015401815 272 r 272 Corynebacterium halotolerans
WP_020935612 269 r 269 Corynebacterium maris
CDA92599     281 S 281
WP_014586008 276 S 276 Methanothrix harundinacea
2DAP_A       269 r 269 Corynebacterium glutamicum
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