Conserved Protein Domain Family
Arm_APC_u3
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pfam16629: Arm_APC_u3 (This model is not part of the current CDD release)
Armadillo-associated region on APC
Arm_APC_u3 is a semi-unstructured region lying immediately downstream of the armadillo fold before the beta-catenin binding motifs, APC_crr, pfam05923, on APC or adenomatous polyposis coli proteins in higher eukaryotes. The function is not known.
Links
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Statistics
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PSSM-Id: 522450
Aligned: 5 rows
Threshold Bit Score: 488.747
Created: 17-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_002936457  734 NRPAKYKDANIMSPGSSVPSLHVRKQKALEAELDAQHLSETFDNIDNLSPKTTHRNKQRHKQNLCSEYVLDSSRH-DDSI 812 
XP_006627072  731 NRPAKYKDANIMSPGSSLPSLHARKQKALIEELDAQHLSETFDNIDNLSPKASHRSKPRHKQNVYSEYVLDSGRHnDDGL 810 
XP_068079834  643 NRPAKYKDANIMSPGSSLPSLHVRKQKALIEELDAQHLSETFDNIDNLSPKASHRVKPRHKHNVYGDY---------DAV 713  zebrafish
NP_001394401  348 NRPAKYKDANIMSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLSPKASHRSKQRHKQSLYGDYVFDTNRH-DDN- 425  human
XP_064412723  732 NRPAKYKDANIMSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLSPKTSHRNKQRQKQNLYSEYALDSGRHnDDSI 811  coelacanth

XP_002936457  813 CRSDNFSLGNLTVLSPYINSTVLP-GSSS--PRPtmEGNRPEKDRE-----RTAGLSNYHSATENsgnSSKRIGVQLSTT 884 
XP_006627072  811 CRPESFNPNNITVLSPYMNTPVLS-SSSSrdSRGnsEGSRAEKDRSldrerRGAGPGGFHPSTDN---TSKRIGMQISTT 886 
XP_068079834  714 CRSDGYNPNGVGVRSPYMNTPVLS-SPSSrdNRGnaESVRAERDRSldrerRG-----FLPDGE----AAKRM-MQIPTS 782  zebrafish
NP_001394401  426 -RSDNFNTGNMTVLSPYLNTTVLP-SSSS--SRGslDSSRSEKDRSle-reRGIGLGNYHPATENpgtSSKR-GLQISTT 499  human
XP_064412723  812 CRSDNFNTGNLTVLSPYLNTTVLQhSSSSreSRG--ESSRSEQDRSld-reRASGPSSFHPATESaasNSKRIGLQMSTT 888  coelacanth

XP_002936457  885 -AQISKVMDEVSNIHMVQEDRSSGSASEMHCMSDERTSQRKPSSnHPHSNPFSFAKGDSSNRGCPVAFMKMEYKmASNDS 963 
XP_006627072  887 aAQIAKVMEEVQSMHISQEERPVGTSTDIHCMQEDISGIRRSST-HTHSNVYAFNKPEHPNRTCPMPYVKMEYR-ASNDS 964 
XP_068079834  783 aAQIAVVMEEVQNMHLGMDDRSAGSTPDPHSVQDDM--IRRQTAvHGHQNIYSYSKTDPSGRPCPMP--KLEYR-ASNDS 857  zebrafish
NP_001394401  500 aAQIAKVMEEVSAIHTSQEDRSSGSTTELHCVTDERNALRRSSAaHTHSNTYNFTKSENSNRTCSMPYAKLEYKrSSNDS 579  human
XP_064412723  889 aAQIAKVMEEVSSLHISHEDRNSSCSADTHCMPDERAILRRASTaQPHSNVHNFNKSESSSRPCPVPYGKMEYKiASNDS 968  coelacanth

XP_002936457  964 LNSVSSTDGYGKRGQVKPSVESYSEDDEGKFGSYGHYPAGLAHKIHSANHMDDNDT 1019
XP_006627072  965 LNSVSSSDGYGKRGQMKPSVDSYSEDDEGKFCSYGKYPADLAHKIHSANHMEDNDG 1020
XP_068079834  858 LNSVNSTDGYGKRGQMKPSVDSYSEDDEGKCCVYRKYPADLAHKIHNANHMEDDNG 913  zebrafish
NP_001394401  580 LNSVSSSDGYGKRGQMKPSIESYSEDDESKFCSYGQYPADLAHKIHSANHMDDNDG 635  human
XP_064412723  969 LNSVSSSDGYGKRGQMKPSIESYSEDDEGKFCNYEKYPADLAHKIHSANHMDDNDG 1024 coelacanth
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