Conserved Protein Domain Family
RhoGEF67_u2
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pfam16614: RhoGEF67_u2 (This model is not part of the current CDD release)
Unstructured region two on RhoGEF 6 and 7
RhoGEF67_u2 is a region of natively unstructured residues on Rho guanine nucleotide exchange factor 6 and 7 proteins. The function is not known. It lies after the PH domain and before the C-terminal coiled-coil.
Links
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Statistics
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PSSM-Id: 522439
Aligned: 4 rows
Threshold Bit Score: 186.454
Created: 17-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_005467501 577 SRGPLEPPKISKPWSLSCLRPAPPLKPSAALGYKERMSYIMKDTSKSPRPMKKFLPgNRRKERKPSDDDIHIRRSTVALE 656
XP_047298631 426 PRGPLEPPQIIKPWSLSCLRPAPPLRPSAALGYKERMSYILKESSKSPKTMKKFLH-KRKTERKPSEEEYVIRKSTAALE 504 human
XP_011606791 459 mWGPLEPPNTPKPWSLSCLRPAPPLRPSAALCYKE-------DLSKSPKSVKKLLP-KRKPERKQSEEEFALRKSTAALE 530 torafugu
XP_005990401 441 SRGPLEPPKIPKPWTLSCLRPAPPLRPSAALGYKERMSYILKDTSKSPRTMKKFLP-KRKTERKPSDDEFILRKSTAALE 519 coelacanth

XP_005467501 657 EDAQILRVIEAYCTGASLHQ 676
XP_047298631 505 EDAQILKVIEAYCTSANFQQ 524 human
XP_011606791 531 EDAQILKVIEAYCTSAKTRQ 550 torafugu
XP_005990401 520 EDAQILKVIEAYCTGASFQQ 539 coelacanth
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